Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384130 | 0.76 | PDE4D (0.39) | TYMPKIF11LMNATHRBMTOR | |
| SCHEMBL3793142 | 0.74 | PDE4D (0.37) | TYMPLMNATHRBMTORMDM2 | |
| SCHEMBL23648799 | 0.73 | PDE3A (0.36) | TYMPKIF11LMNATHRBMTOR | |
| SCHEMBL28280335 | 0.73 | BACE1 (0.32) | TYMPKIF11 | |
| SCHEMBL383850 | 0.72 | L3MBTL1 (0.31) | ST6GAL1TYMP | |
| SCHEMBL1739169 | 0.72 | PDE3A (0.32) | TYMPKIF11LMNATHRBMTOR | |
| SCHEMBL9083312 | 0.70 | PDE3A (0.39) | ST6GAL1LMNATHRBMTORMDM2 | |
| SCHEMBL5318029 | 0.70 | BACE1 (0.36) | NT5EST6GAL1TYMPKIF11 | |
| SCHEMBL2474292 | 0.70 | — | — | |
| SCHEMBL2474312 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010108140-A1 | SUBSTITUTED NUCLEOSIDE AND NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. (US) | 2010-09-23 | — | — | WO | disclosed |