Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3793142 | 0.89 | PDE4D (0.37) | PDE4DPDE3ASLC29A1LMNATHRB | |
| SCHEMBL383850 | 0.87 | L3MBTL1 (0.31) | PDE4DPDE3ASLC29A1BACE1TYMP | |
| SCHEMBL9083312 | 0.83 | PDE3A (0.39) | PDE4DPDE3ASLC29A1LMNATHRB | |
| SCHEMBL23648799 | 0.80 | PDE3A (0.36) | PDE4DPDE3ASLC29A1LMNATHRB | |
| SCHEMBL1739169 | 0.77 | PDE3A (0.32) | PDE4DPDE3ASLC29A1LMNATHRB | |
| SCHEMBL3789736 | 0.76 | NT5E (0.31) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL29834201 | 0.74 | P2RY14 (0.34) | SLC29A1TYMP | |
| SCHEMBL28862842 | 0.73 | PDE4D (0.30) | PDE4DPDE3ASLC29A1LMNATHRB | |
| SCHEMBL11430666 | 0.72 | LMNA (0.45) | PDE4DPDE3ASLC29A1LMNATHRB | |
| SCHEMBL9752462 | 0.72 | LMNA (0.38) | PDE4DPDE3ASLC29A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408306-A1 | SUBSTITUTED NUCLEOSIDE AND NUCLEOTIDE ANALOGS | Alios Biopharma, Inc. (US) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010108140-A1 | SUBSTITUTED NUCLEOSIDE AND NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. (US) | 2010-09-23 | — | — | WO | disclosed |