Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL942285 | 0.84 | ALDH1A1 (0.46) | KDM4EALDH1A1PLAAT5PLAAT4PLAAT3 | |
| SCHEMBL149370 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL3148805 | 0.80 | MMP1 (0.41) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL27993992 | 0.80 | MMP1 (0.41) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Methylamine SCHEMBL2363145 | 0.78 | MMP1 (0.40) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28010702 | 0.78 | MMP1 (0.40) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Dimethylamine SCHEMBL42843 | 0.78 | MMP1 (0.40) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Phenol SCHEMBL28968646 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1SMN1; SMN2KMT2ALMNA | |
| Phenol SCHEMBL8803835 | 0.77 | BCAT2 (0.47) | KDM4EALDH1A1KMT2AL3MBTL1LMNA | |
| SCHEMBL1027805 | 0.77 | SMN1; SMN2 (0.64) | KDM4EALDH1A1PLAAT5PLAAT4PLAAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507613-A | Bispecific antagonists of retinol binding protein 4 which stabilize transthyretin tetramer, their preparation and use in the treatment of common age-related complications | 纽约哥伦比亚大学理事会 | 2023-07-28 | — | — | CN | disclosed |
| CN-109195947-A | novel inhibitors of hypnotic proteins α and beta | 弗劳恩霍夫应用研究促进协会 | 2019-01-11 | — | — | CN | disclosed |
| WO-2018187519-A1 | SYNERGISTIC COMBINATION OF NUCLEIC ACID OLIGONUCLEOTIDES AND TAXANE CHEMOTHERAPEUTICS | JIVANA BIOTECHNOLOGY INC. (US) | 2018-10-11 | — | — | WO | disclosed |
| CN-105188729-A | Conjugates for protection from nephrotoxic active substances | MERCK PATENT GMBH | 2015-12-23 | — | — | CN | disclosed |
| CN-105188728-A | Peptides and peptide-active ingredient-conjugate for renal drug-targeting | MERCK PATENT GMBH | 2015-12-23 | — | — | CN | disclosed |
| EP-2260839-A2 | Combination therapy using 1-aminocyclohexane derivatives and acetylcholinesterase inhibitors | Merz Pharma GmbH & Co. KGaA (DE) | 2010-12-15 | — | — | EP | disclosed |
| CN-1391575-A | Nitrogen containing heterobicycles as factor XA inhibitors | DU PONT PHARM CO (US) | 2003-01-15 | — | — | CN | disclosed |