SCHEMBL379018

SCHEMBL379018

CC(C)CC(O)CNCCN1CCNC1=O

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.43
RAB9A P51151 1/20 0.43
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 2/20 0.39
LMNA P02545 1/20 0.39
RET P07949 1/20 0.37
KDR P35968 1/20 0.37
CREBBP Q92793 1/20 0.36
PER2 O15055 3/20 0.36
SCN9A Q15858 5/20 0.34
HPGDS O60760 1/20 0.33
CRY2 Q49AN0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17485954 0.85 KMT2A (0.46) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL2578623 0.81 KMT2A (0.41) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL471729 0.77 ALDH1A1 (0.50) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL22030392 0.75 ALDH1A1 (0.49) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL98511 0.75 RAB9A (0.36) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL28922453 0.74 KMT2A (0.38) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL25555005 0.74 KMT2A (0.44) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL2291952 0.73 KMT2A (0.39) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL12871170 0.72 KMT2A (0.48) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL20734660 0.72 KMT2A (0.48) KMT2ARAB9AALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1801158-B1 Water-based process for the preparation of polymer-clay nanocomposites GOODYEAR TIRE & RUBBER (US) 2012-01-25 EP disclosed
EP-1778770-B1 MODIFIED SURFACE MATERIAL, METHOD FOR PREPARING SAME AND USES THEREOF UNIV PARIS 7 DENIS DIDEROT (FR) 2011-11-02 EP disclosed
US-7625985-B1 Water-based process for the preparation of polymer-clay nanocomposites THE GOODYEAR TIRE & RUBBER COMPANY (US) 2009-12-01 US disclosed
US-7259217-B2 Controlled-architecture polymers and use thereof as separation media SYMYX TECHNOLOGIES, INC. (US) 2007-08-21 US disclosed
EP-1801158-A1 Water-based process for the preparation of polymer-clay nanocomposites THE GOODYEAR TIRE & RUBBER COMPANY (US) 2007-06-27 EP disclosed
US-7205161-B2 Polymer brushes for immobilizing molecules to a surface or substrate having improved stability SYMYX TECHNOLOGIES, INC. (US) 2007-04-17 US disclosed
US-20060128917-A1 Controlled-architecture polymers and use thereof as separation media SYMYX TECHNOLOGIES, INC. 2006-06-15 US disclosed
EP-1208126-B1 POLYMER BRUSHES FOR IMMOBILIZING MOLECULES TO A SURFACE OR SUBSTRATE, WHERE THE POLYMERS HAVE WATER-SOLUBLE OR WATER-DISPERSIBLE SEGMENTS AND PROBES BONDED THERETO SYMYX TECHNOLOGIES INC (US) 2006-04-12 EP disclosed
US-20050158879-A1 Polymer brushes for immobilizing molecules to a surface and having water-soluble or water-dispersible segments therein and probes bonded thereto SYMYX TECHNOLOGIES, INC. (US) 2005-07-21 US disclosed
US-6833276-B2 Detectors for quantative, qualitative analysis SYMYX TECHNOLOGIES, INC. 2004-12-21 US disclosed
WO-2001002452-A9 POLYMER BRUSHES FOR IMMOBILIZING MOLECULES TO A SURFACE OR SUBSTRATE, WHERE THE POLYMERS HAVE WATER-SOLUBLE OR WATER-DISPERSIBLE SEGMENTS AND PROBES BONDED THERETO SYMYX TECHNOLOGIES INC (US) 2002-07-25 WO disclosed
EP-1208126-A1 POLYMER BRUSHES FOR IMMOBILIZING MOLECULES TO A SURFACE OR SUBSTRATE, WHERE THE POLYMERS HAVE WATER-SOLUBLE OR WATER-DISPERSIBLE SEGMENTS AND PROBES BONDED THERETO Symyx Technologies, Inc. (US) 2002-05-29 EP disclosed
US-20020061988-A1 CONTROLLED STABLE FREE RADICAL EMULSION POLYMERIZATION PROCESSES FREESLATE, INC. 2002-05-23 US disclosed
US-20020013430-A1 Controlled free radical emulsion and water-based polymerizations and seeded methodologies FREESLATE, INC. 2002-01-31 US disclosed
US-20020010267-A1 Polymer segment characterized by a high degree of control over molecular weight, particle size, polydispersity; especially produced using a nitroxide control agent that can be a stable free radical or as an adduct with the initiator SYMYX TECHNOLOGIES, INC., A DELAWARE CORPORATION 2002-01-24 US disclosed
US-20020001845-A1 Polymer brushes for immobilizing molecules to a surface and having water-soluble or water-dispersible segments therein and probes bonded thereto FREESLATE, INC. 2002-01-03 US disclosed
EP-1165625-A1 CONTROLLED FREE RADICAL EMULSION AND WATER-BASED POLYMERIZATIONS AND SEEDED METHODOLOGIES Symyx Technologies, Inc. (US) 2002-01-02 EP disclosed
WO-2001009204-A2 CONTROLLED-ARCHITECTURE POLYMERS AND USE THEREOF AS SEPARATION MEDIA SYMYX TECHNOLOGIES, INC. (US) 2001-02-08 WO disclosed
WO-2001002452-A1 POLYMER BRUSHES FOR IMMOBILIZING MOLECULES TO A SURFACE OR SUBSTRATE, WHERE THE POLYMERS HAVE WATER-SOLUBLE OR WATER-DISPERSIBLE SEGMENTS AND PROBES BONDED THERETO SYMYX TECHNOLOGIES, INC. (US) 2001-01-11 WO disclosed
WO-2000053640-A1 CONTROLLED FREE RADICAL EMULSION AND WATER-BASED POLYMERIZATIONS AND SEEDED METHODOLOGIES SYMYX TECHNOLOGIES, INC. (US) 2000-09-14 WO disclosed