SCHEMBL471729

SCHEMBL471729

O=C1NCCN1CCNCCN1CCNC1=O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
KMT2A Q03164 4/20 0.50
RAB9A P51151 1/20 0.50
KDM4E B2RXH2 2/20 0.48
LMNA P02545 1/20 0.48
SCN9A Q15858 7/20 0.43
POLB P06746 2/20 0.43
CREBBP Q92793 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
MEN1 O00255 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
RET P07949 1/20 0.39
KDR P35968 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22030392 0.98 ALDH1A1 (0.49) ALDH1A1KMT2ARAB9AKDM4ELMNA
SCHEMBL18711241 0.91 KMT2A (0.48) ALDH1A1KMT2ARAB9AKDM4ELMNA
SCHEMBL20734660 0.91 KMT2A (0.48) ALDH1A1KMT2ARAB9AKDM4ELMNA
SCHEMBL259671 0.91 ACE2 (0.47) ALDH1A1KMT2ARAB9AKDM4ELMNA
SCHEMBL21923029 0.91 ALDH1A1 (0.44) ALDH1A1KMT2ARAB9AKDM4ELMNA
SCHEMBL9607158 0.89 KMT2A (0.47) ALDH1A1KMT2ARAB9AKDM4ELMNA
SCHEMBL261011 0.89 ACE2 (0.46) ALDH1A1KMT2ARAB9AKDM4ELMNA
SCHEMBL20655943 0.89 ACE2 (0.46) ALDH1A1KMT2ARAB9AKDM4ELMNA
SCHEMBL9607157 0.89 KMT2A (0.47) ALDH1A1KMT2ARAB9AKDM4ELMNA
SCHEMBL6284635 0.88 KMT2A (0.49) ALDH1A1KMT2ARAB9AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11697735-B2 Solid oleaginous compositions TOTAL MARKETING SERVICES (FR) 2023-07-11 US disclosed
US-11697735-B2 Solid oleaginous compositions TOTAL MARKETING SERVICES (FR) 2023-07-11 US disclosed
US-11365317-B2 Solid binders TOTAL MARKETING SERVICES (FR) 2022-06-21 US disclosed
EP-3612616-B1 SOLID BITUMEN AT AMBIENT TEMPERATURE TOTAL MARKETING SERVICES (FR) 2022-06-01 EP disclosed
US-11339116-B2 Reactive separation process to convert cyclic alkylene ureas into their corresponding alkylene amines NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2022-05-24 US disclosed
US-11332606-B2 Clear binder that is solid when cold TOTAL MARKETING SERVICES (FR) 2022-05-17 US disclosed
EP-3510103-B1 CLEAR SOLID COLD BINDER TOTAL MARKETING SERVICES (FR) 2022-02-16 EP disclosed
US-11242287-B2 Bitumen which is solid at ambient temperature TOTAL MARKETING SERVICES (FR) 2022-02-08 US disclosed
US-11214549-B2 Process for making higher ethylene amines NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2022-01-04 US disclosed
US-11198105-B2 Method for manufacturing material in the form of granules that can be used as road binder or sealing binder and device for manufacturing same TOTAL MARKETING SERVICES (FR) 2021-12-14 US disclosed
US-7750113-B2 Supramolecular polymers ARKEMA FRANCE (FR) 2010-07-06 US disclosed
WO-2008107551-A2 BITUMINOUS COMPOSITION WITH THERMOREVERSIBLE PROPERTIES TOTAL RAFFINAGE MARKETING (FR) 2008-09-12 WO disclosed
US-20080167442-A1 SUPRAMOLECULAR POLYMERS ARKEMA FRANCE (FR) 2008-07-10 US disclosed
US-20080167442-A1 SUPRAMOLECULAR POLYMERS ARKEMA FRANCE (FR) 2008-07-10 US disclosed
US-7348397-B2 Supramolecular polymers ARKEMA FRANCE (FR) 2008-03-25 US disclosed
US-7348397-B2 Supramolecular polymers ARKEMA FRANCE (FR) 2008-03-25 US disclosed
US-7250487-B2 Supramolecular polymers ARKEMA FRANCE (FR) 2007-07-31 US disclosed
US-7250487-B2 Supramolecular polymers ARKEMA FRANCE (FR) 2007-07-31 US disclosed
US-20070123694-A1 Supramolecular polymers TOURNILHAC FRANCOIS-GENES 2007-05-31 US disclosed
US-20070123694-A1 Supramolecular polymers TOURNILHAC FRANCOIS-GENES 2007-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11339116-B2 Reactive separation process to convert cyclic alkylene ureas into their corresponding alkylene amines UTP20, CGAS, UMPS ALDH1A1 2104/4885KMT2A 2288/4885RAB9A 3591/4885
US-11214549-B2 Process for making higher ethylene amines HRH4, HRH3, HRH1 ALDH1A1 1957/4885KMT2A 997/4885RAB9A 1368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.