SCHEMBL379019

SCHEMBL379019

CCCCC(O)CNC(C)N1CCNC1=O

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.37
NAAA Q02083 1/20 0.37
ATG4B Q9Y4P1 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
GNAI3 P08754 1/20 0.31
GNAO1 P09471 1/20 0.31
GNAI1 P63096 1/20 0.31
GPR84 Q9NQS5 4/20 0.30
ADRB2 P07550 4/20 0.30
CCR2 P41597 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24772662 0.75 FAAH (0.41) FAAHNAAACCR2
SCHEMBL1305192 0.74 CYP2D6 (0.38) ADRB2
SCHEMBL2578623 0.72 KMT2A (0.41) FAAHNAAA
SCHEMBL23921699 0.70 FAAH (0.51) FAAHNAAAGNAI3GNAO1GNAI1
SCHEMBL25132003 0.70 FAAH (0.51) FAAHNAAAGNAI3GNAO1GNAI1
SCHEMBL25687608 0.69 FAAH (0.46) FAAHNAAAGNAI3GNAO1GNAI1
SCHEMBL11262207 0.69 GPR84 (0.34) FAAHGPR84
SCHEMBL11270382 0.69 GPR84 (0.34) FAAHGPR84
SCHEMBL19288356 0.68 GAA (0.38) FAAHNAAA
SCHEMBL1943095 0.68 ACE2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1801158-B1 Water-based process for the preparation of polymer-clay nanocomposites GOODYEAR TIRE & RUBBER (US) 2012-01-25 EP disclosed
US-7625985-B1 Water-based process for the preparation of polymer-clay nanocomposites THE GOODYEAR TIRE & RUBBER COMPANY (US) 2009-12-01 US disclosed
EP-1801158-A1 Water-based process for the preparation of polymer-clay nanocomposites THE GOODYEAR TIRE & RUBBER COMPANY (US) 2007-06-27 EP disclosed