SCHEMBL1943095

SCHEMBL1943095

CC(NCCNCCN)N1CCNC1=O

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACE2 Q9BYF1 1/20 0.33
LMNA P02545 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32
ALOX15 P16050 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2480876 0.75 CA12 (0.37) ACE2LMNATDP1CA12CA1
SCHEMBL11547492 0.75 CA12 (0.37) ACE2LMNATDP1CA12CA1
SCHEMBL27815386 0.73 LMNA (0.34) ACE2LMNATDP1CA12CA1
SCHEMBL29139993 0.70 CA12 (0.38) ACE2LMNATDP1CA12CA1
SCHEMBL20655943 0.70 ACE2 (0.46) ACE2LMNATDP1CA12CA1
SCHEMBL261011 0.70 ACE2 (0.46) ACE2LMNATDP1CA12CA1
SCHEMBL10708174 0.69 CA12 (0.41) ACE2LMNATDP1CA12CA1
SCHEMBL20733249 0.69 TOP2A (0.37) ALDH1A1
SCHEMBL259671 0.68 ACE2 (0.47) ACE2LMNACA12CA6CA7
SCHEMBL379019 0.68 FAAH (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492495-B2 Polymeric additives obtained by salification of copolymers ARKEMA FRANCE (FR) 2013-07-23 US claimed
US-20130005914-A1 STYRENE/ANHYDRIDE POLYMERIC MATERIAL AND GRAFT HAVING ENHANCED PROPERTIES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2013-01-03 US claimed
US-8242207-B2 Styrene/anhydride polymeric material and graft having enhanced properties ARKEMA FRANCE (FR) 2012-08-14 US claimed
CN-102131846-A Method for synthesizing supramolecular materials ARKEMA FRANCE 2011-07-20 CN claimed
EP-2235070-B1 POLYMERIC ADDITIVES OBTAINED BY SALIFICATION OF COPOLYMERS ARKEMA FRANCE (FR) 2011-06-15 EP claimed
US-20110059280-A1 METHOD FOR SYNTHESIZING SUPRAMOLECULAR MATERIALS ARKEMA FRANCE 2011-03-10 US claimed
CN-101918458-A Polymeric additives obtained by salification of copolymers ARKEMA FRANCE 2010-12-15 CN claimed
US-20100273965-A1 POLYMERIC ADDITIVES OBTAINED BY SALIFICATION OF COPOLYMERS ARKEMA FRANCE (FR) 2010-10-28 US claimed
EP-2834289-A1 MONOMERS BEARING ASSOCIATIVE GROUPS FOR THE SYNTHESIS OF SUPRAMOLECULAR POLYCONDENSATES Arkema France (FR) 2015-02-11 EP disclosed
CN-102131846-B Method for synthesizing supramolecular materials ARKEMA FRANCE 2014-01-15 CN disclosed
WO-2013150221-A1 MONOMERS BEARING ASSOCIATIVE GROUPS FOR THE SYNTHESIS OF SUPRAMOLECULAR POLYCONDENSATES ARKEMA FRANCE (FR) 2013-10-10 WO disclosed
US-20130248087-A1 PROCESS FOR PRODUCING FIBROUS MATERIAL PRE-IMPREGNATED WITH THERMOSETTING POLYMER ARKEMA FRANCE (FR) 2013-09-26 US disclosed
US-8536281-B2 Method for synthesizing supramolecular materials ARKEMA FRANCE (FR) 2013-09-17 US disclosed
US-8492495-B2 Polymeric additives obtained by salification of copolymers ARKEMA FRANCE (FR) 2013-07-23 US disclosed
CN-102131846-A Method for synthesizing supramolecular materials ARKEMA FRANCE 2011-07-20 CN disclosed
EP-2235070-B1 POLYMERIC ADDITIVES OBTAINED BY SALIFICATION OF COPOLYMERS ARKEMA FRANCE (FR) 2011-06-15 EP disclosed
US-20110059280-A1 METHOD FOR SYNTHESIZING SUPRAMOLECULAR MATERIALS ARKEMA FRANCE 2011-03-10 US disclosed
CN-101918458-A Polymeric additives obtained by salification of copolymers ARKEMA FRANCE 2010-12-15 CN disclosed
US-20100273965-A1 POLYMERIC ADDITIVES OBTAINED BY SALIFICATION OF COPOLYMERS ARKEMA FRANCE (FR) 2010-10-28 US disclosed