Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 2/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8166926 | 0.92 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1HSD17B10SMN1; SMN2CYP3A4 | |
| SCHEMBL398474 | 0.86 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1HSD17B10SMN1; SMN2CYP3A4 | |
| SCHEMBL3644248 | 0.86 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1HSD17B10SMN1; SMN2CYP3A4 | |
| SCHEMBL29781768 | 0.82 | CYP3A4 (0.48) | ALDH1A1L3MBTL1HSD17B10SMN1; SMN2CYP3A4 | |
| SCHEMBL19208273 | 0.82 | CYP3A4 (0.48) | ALDH1A1L3MBTL1HSD17B10SMN1; SMN2CYP3A4 | |
| SCHEMBL12480566 | 0.82 | TSHR (0.50) | ALDH1A1L3MBTL1HSD17B10SMN1; SMN2CYP3A4 | |
| SCHEMBL3785815 | 0.81 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1HSD17B10SMN1; SMN2CYP3A4 | |
| SCHEMBL31607672 | 0.81 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1HSD17B10SMN1; SMN2CYP3A4 | |
| SCHEMBL169281 | 0.81 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1HSD17B10SMN1; SMN2CYP3A4 | |
| Hydrochloric Acid SCHEMBL17023694 | 0.81 | TSHR (0.48) | ALDH1A1L3MBTL1HSD17B10SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | ALDH1A1 4339/4885L3MBTL1 3838/4885HSD17B10 1100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.