SCHEMBL379055

SCHEMBL379055

[c]1c(-c2ccccc2)cccc1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
RAB9A P51151 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPK1 P28482 2/20 0.36
NPC1 O15118 1/20 0.36
TAAR1 Q96RJ0 2/20 0.36
MAOA P21397 1/20 0.36
NOTUM Q6P988 2/20 0.35
HSD17B10 Q99714 2/20 0.35
BCL2L1 Q07817 2/20 0.35
CYP1A2 P05177 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35
CYP3A4 P08684 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MMP3 P08254 1/20 0.35
BACE1 P56817 1/20 0.33
ASIC3 Q9UHC3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6761031 0.87 MEN1 (0.46) ALDH1A1MEN1KMT2AMAPK1TAAR1
SCHEMBL723026 0.86 ALDH1A1 (0.40) ALDH1A1RAB9AMEN1KMT2AMAPK1
SCHEMBL3323756 0.85 ALDH1A1 (0.39) ALDH1A1MAPK1HSD17B10BCL2L1TDP1
SCHEMBL11345498 0.84 ALDH1A1 (0.38) ALDH1A1RAB9AMEN1KMT2AMAPK1
SCHEMBL7951300 0.83 ALDH1A1 (0.33) ALDH1A1RAB9AMEN1KMT2A
SCHEMBL335715 0.82 ALDH1A1 (0.36) ALDH1A1RAB9AMEN1KMT2ATAAR1
SCHEMBL6437984 0.82 CYP1A2 (0.39) ALDH1A1RAB9AMEN1KMT2ANPC1
SCHEMBL3774002 0.82 BCL2L1 (0.39) ALDH1A1RAB9AMEN1KMT2AHSD17B10
SCHEMBL1803708 0.82 ALDH1A1 (0.36) ALDH1A1RAB9AMEN1KMT2ANPC1
SCHEMBL8586499 0.82 MAOA (0.39) ALDH1A1RAB9AMEN1KMT2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1396 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344695-A Hydroxyl-enriched cycloolefin copolymer long afterglow material and application thereof 重庆理工大学 2024-07-16 CN claimed
US-20240147837-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-05-02 US claimed
CN-111408411-B Catalyst composition, preparation method thereof and application thereof in reaction of synthesizing 1-butene by ethylene selective dimerization 中国石油化工股份有限公司 2024-02-13 CN claimed
WO-2023213759-A1 POLYMERS CONTAINING SPECIALLY SUBSTITUTED TRIARYLAMINE UNITS AND ELECTROLUMINESCENT DEVICES CONTAINING SAID POLYMERS MERCK PATENT GMBH (DE) 2023-11-09 WO claimed
CN-116693734-A Preparation method and application of trans-1, 2-poly-ocimene 湖北航天化学技术研究所 2023-09-05 CN claimed
CN-116693733-A Isotactic cis-1, 4-poly-ocimene and preparation method and application thereof 中国科学院长春应用化学研究所 2023-09-05 CN claimed
CN-116554372-A Preparation method of low-entanglement ultra-high molecular weight polyethylene 中国科学院长春应用化学研究所 2023-08-08 CN claimed
US-20230240140-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-07-27 US claimed
CN-111408412-B Catalyst composition, preparation method thereof and application thereof in reaction of synthesizing 1-butene by ethylene selective dimerization 中国石油化工股份有限公司 2023-05-09 CN claimed
CN-111408405-B Catalyst composition, preparation method thereof and application thereof in reaction for synthesizing 1-butene through selective dimerization of ethylene 中国石油化工股份有限公司 2023-03-28 CN claimed
EP-0710638-B1 Rhenium and aluminium containing catalytic compositions, their preparation and use for the metathesis of olefins INST FRANCAIS DU PETROLE (FR) 1999-02-10 EP claimed
EP-0889910-A1 SOLUTION POLYMERIZATION PROCESS WITH DISPERSED CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 1999-01-13 EP claimed
EP-0710639-B1 New supported compounds containing rhenium and aluminium, their preparation and use for the metathesis of olefins INST FRANCAIS DU PETROLE (FR) 1998-08-19 EP claimed
US-5747408-A Supported catalysts containing rhenium and aluminium, preparation thereof and use thereof for the metathesis of olefins INSTITUT FRANCAIS DU PETROLE (FR) 1998-05-05 US claimed
US-5747409-A Catalytic compositions based on compounds of rhenium and aluminium, preparation thereof and use thereof for the metathesis of olefins INSTITUT FRANCAIS DU PETROLE (FR) 1998-05-05 US claimed
WO-1997035892-A1 SOLUTION POLYMERIZATION PROCESS WITH DISPERSED CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 1997-10-02 WO claimed
WO-1997021678-A1 CARBAMIC ACID DERIVATIVES AS LEUKOTRIENE ANTAGONISTS BAYER AKTIENGESELLSCHAFT (DE) 1997-06-19 WO claimed
US-5596115-A Compounds of rhenium and aluminium, preparation thereof and use thereof as catalysts INSTITUT FRANCAIS DU PETROLE (FR) 1997-01-21 US claimed
US-5530162-A Process for the hydrogenation of aryl phosphines and products obtained therefrom RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1996-06-25 US claimed
WO-1993021192-A1 PROCESS FOR THE HYDROGENATION OF ARYL PHOSPHINES AND PRODUCTS OBTTAINED THEREFROM RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1993-10-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240147837-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CHRM1 ALDH1A1 1845/4885RAB9A 1715/4885MEN1 3642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.