SCHEMBL1803708

SCHEMBL1803708

Cc1[c]c(-c2ccccc2)ccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
TSHR P16473 2/20 0.33
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
RAB9A P51151 3/20 0.32
NPC1 O15118 2/20 0.32
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP2A6 P11509 1/20 0.31
CYP2B6 P20813 1/20 0.31
SLC22A2 O15244 1/20 0.31
SLC22A1 O15245 1/20 0.31
SLC22A3 O75751 1/20 0.31
SLC6A4 P31645 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29104461 0.84 ACHE (0.36) ALDH1A1TSHRLMNAALOX12ACHE
SCHEMBL379055 0.82 ALDH1A1 (0.47) ALDH1A1LMNARAB9ANPC1MEN1
SCHEMBL7951323 0.82 ACHE (0.33) ALDH1A1TSHRACHECYP2A6
SCHEMBL723358 0.81 ALDH1A1 (0.36) ALDH1A1TSHRLMNAALOX12ACHE
SCHEMBL2937510 0.80 CYP1A2 (0.39) ALDH1A1TSHRLMNAL3MBTL1RAB9A
SCHEMBL2942465 0.77 ABL1 (0.47) ALDH1A1ACHECYP2A6CYP2B6
SCHEMBL29104462 0.77 HSD17B1 (0.44) ALDH1A1TSHRRAB9ANPC1CYP2A6
SCHEMBL3994708 0.77 TP53 (0.38) ALDH1A1RAB9ANPC1CYP2A6MAPT
SCHEMBL11345498 0.73 ALDH1A1 (0.38) ALDH1A1LMNARAB9ANPC1MEN1
SCHEMBL2703844 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240114784-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-04-04 US claimed
EP-4270508-A1 ORGANIC LIGHT EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-11-01 EP claimed
US-20230232700-A1 METHOD FOR PATTERNING A COATING ON A SURFACE AND DEVICE INCLUDING A PATTERNED COATING OTI LUMIONICS INC. (CA) 2023-07-20 US claimed
US-20230165124-A1 METHOD FOR PATTERNING A COATING ON A SURFACE AND DEVICE INCLUDING A PATTERNED COATING OTI LUMIONICS INC. (CA) 2023-05-25 US claimed
US-11581487-B2 Patterned conductive coating for surface of an opto-electronic device OTI LUMIONICS INC. (CA) 2023-02-14 US claimed
CN-106496130-A A kind of methyl ketone derivatives and preparation method and application 苏州大学 2017-03-15 CN claimed
EP-0798291-B1 NOVEL 1,3-DIALKYLUREA DERIVATIVES SANTEN PHARMACEUTICAL CO LTD (JP) 2002-09-11 EP claimed
US-5968980-A ENDOPEPTIDASE 24.11 INHIBITORS SANTEN PHARMACEUTICAL CO., LTD. (JP) 1999-10-19 US claimed
EP-0798291-A1 NOVEL 1,3-DIALKYLUREA DERIVATIVES SANTEN PHARMACEUTICAL CO., LTD. (JP) 1997-10-01 EP claimed
EP-4365180-A1 RARE EARTH COMPLEX Tosoh Corporation (JP) 2024-05-08 EP disclosed
US-20240114784-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-04-04 US disclosed
CN-117044428-A Lateral current suppressing material, carbazole compound, hole injection layer, and organic electroluminescent element 东曹株式会社 2023-11-10 CN disclosed
EP-4270508-A1 ORGANIC LIGHT EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-11-01 EP disclosed
US-11785831-B2 Method for patterning a coating on a surface and device including a patterned coating OTI LUMIONICS INC. (CA) 2023-10-10 US disclosed
EP-0055925-A2 Alkyl N-arylsulfenyl-N-diaryloxy-phosphinylmethylglycinates and their use as herbicides MONSANTO COMPANY (US) 1982-07-14 EP disclosed
US-4300943-A Ester derivatives of N-arylthio-N-phosphonomethylglycinonitrile MONSANTO COMPANY (US) 1981-11-17 US disclosed
US-4290870-A 5-ISOXOLONE, AROMATIC CARBONYL, DIALKYLAMINO AROMATIC CARBONYL OR FUJI PHOTO FILM CO., LTD. (JP) 1981-09-22 US disclosed
US-4252554-A Herbicidal ester derivatives of N-arylthio-N-phosphonomethylglycinonitrile MONSANTO COMPANY (US) 1981-02-24 US disclosed
US-4224225-A PHOTOPOLYMERIZATION INITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1980-09-23 US disclosed
US-4148658-A BENZOYLMETHYLENE-BENSOTHIAZOLYIDEND-THIAZOLIDONE COMPOUND, AMINE, AND AMINOARYLCARBONYL COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1979-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240114784-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYBA ALDH1A1 8/4885TSHR 4436/4885LMNA 3581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.