SCHEMBL3790672

SCHEMBL3790672

C=CC(=O)Oc1ccc2c(=O)c3ccccc3sc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
MAPT P10636 7/20 0.50
RAB9A P51151 5/20 0.50
NPC1 O15118 4/20 0.50
KDM4E B2RXH2 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
PTPN7 P35236 1/20 0.39
DUSP3 P51452 1/20 0.39
PTPN12 Q05209 1/20 0.39
PTPN22 Q9Y2R2 1/20 0.39
HCRTR1 O43613 2/20 0.39
POLB P06746 2/20 0.39
LMNA P02545 1/20 0.39
HPGD P15428 5/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31120514 1.00 ALDH1A1 (0.50) ALDH1A1MAPTRAB9ANPC1KDM4E
SCHEMBL30998139 0.92 MAPT (0.61) ALDH1A1MAPTRAB9ANPC1KDM4E
SCHEMBL85778 0.92 MAPT (0.61) ALDH1A1MAPTRAB9ANPC1KDM4E
SCHEMBL18533259 0.85 ALDH1A1 (0.47) ALDH1A1MAPTRAB9ANPC1KDM4E
SCHEMBL25852962 0.85 THRB (0.44) ALDH1A1MAPTKDM4EPTPN7DUSP3
SCHEMBL10600228 0.84 MAPT (0.54) ALDH1A1MAPTRAB9ANPC1KDM4E
SCHEMBL11994246 0.84 THRB (0.54) ALDH1A1MAPTRAB9ANPC1KDM4E
SCHEMBL16708721 0.84 KDM4E (0.49) ALDH1A1MAPTRAB9ANPC1KDM4E
SCHEMBL25026543 0.83 MAPT (0.41) ALDH1A1MAPTRAB9ANPC1KDM4E
SCHEMBL27660054 0.83 MAPT (0.56) ALDH1A1MAPTRAB9ANPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8414982-B2 Process for the production of strongly adherent coatings BASF SE (DE) 2013-04-09 US disclosed
EP-1836002-B1 PROCESS FOR THE PRODUCTION OF STRONGLY ADHERENT COATINGS BASF SE (DE) 2012-08-29 EP disclosed
US-20100178512-A1 CHANGING SURFACE PROPERTIES BY FUNCTIONALIZED NANOPARTICLES CIBA CORPORATION (US) 2010-07-15 US disclosed
US-20090092768-A1 Process for the Production of Strongly Adherent Coatings CIBA SPECIALTY CHEMICALS CORP. 2009-04-09 US disclosed
US-7455891-B2 Process for the production of strongly adherent coatings CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-11-25 US disclosed
US-20070128441-A1 Process for the production of strongly adherent coatings CIBA SPECIALTY CHEMICALS CORP. 2007-06-07 US disclosed
EP-1772479-A1 Silicon coated release substrate Ciba Specialty Chemicals Holding Inc. (CH) 2007-04-11 EP disclosed
US-20060257575-A1 Process for the production of strongly adherent coatings CIBA SPECIALTY CHEMICALS CORP. 2006-11-16 US disclosed
EP-1472009-B1 PROCESS FOR THE PRODUCTION OF STRONGLY ADHERENT COATINGS CIBA SC HOLDING AG (CH) 2005-12-28 EP disclosed
US-20050147919-A1 Process for the production of strongly adherent coatings CIBA SPECIALTY CHEMICALS CORP. 2005-07-07 US disclosed
EP-1498189-A1 Anti-fog coatings on thermoplastic substrates Ciba SC Holding AG (CH) 2005-01-19 EP disclosed
EP-1135219-B1 METHOD FOR PRODUCING ADHESIVE SURFACE COATINGS CIBA SC HOLDING AG (CH) 2004-01-28 EP disclosed
US-6548121-B1 Subjecting substrate to action of low-temperature plasma discharge or radiation, applying photoinitiator containing ethylenically unsaturated group, curing, depositing metal or oxide CIBA SPECIALTY CHEMICALS CORPORATION 2003-04-15 US disclosed