Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28811116 | 0.87 | CYP4F2 (0.52) | ALOX5OR51E2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL18232227 | 0.86 | PTPN1 (0.43) | ALOX5OR51E2KMT2AMAPTALDH1A1 | |
| SCHEMBL6407212 | 0.85 | ALDH1A1 (0.49) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL30185945 | 0.84 | CDK1 (0.59) | ALOX5OR51E2ALDH1A1GAAPTPN1 | |
| SCHEMBL15543678 | 0.84 | CDK1 (0.59) | ALOX5OR51E2ALDH1A1GAAPTPN1 | |
| SCHEMBL3940302 | 0.83 | KMT2A (0.59) | ALOX5OR51E2MEN1KMT2AMAPT | |
| SCHEMBL931031 | 0.82 | MAPT (0.48) | ALOX5MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27836800 | 0.82 | PTPN1 (0.43) | ALOX5OR51E2MAPTPOLBPTPN1 | |
| SCHEMBL8417759 | 0.82 | PTPN1 (0.42) | ALOX5OR51E2MEN1KMT2AMAPT | |
| SCHEMBL20730189 | 0.81 | ERN1 (0.48) | MEN1KMT2AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113174377-B | Carbonyl reductase, mutant and application of carbonyl reductase in preparation of diltiazem intermediate | 华东理工大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-113174377-A | Carbonyl reductase, mutant and application of carbonyl reductase and mutant in preparation of diltiazem intermediate | 华东理工大学 | 2021-07-27 | — | — | CN | disclosed |
| US-7705040-B2 | compositions which specifically react with peroxynitrite rather than other reactive oxygen species and reactive nitrogen species; for measuring peroxynitrite in a sample; high-throughput screening fluorescent methods for detecting peroxynitrite | THE UNIVERSITY OF HONG KONG (CN) | 2010-04-27 | — | — | US | disclosed |
| US-7705040-B2 | compositions which specifically react with peroxynitrite rather than other reactive oxygen species and reactive nitrogen species; for measuring peroxynitrite in a sample; high-throughput screening fluorescent methods for detecting peroxynitrite | THE UNIVERSITY OF HONG KONG (CN) | 2010-04-27 | — | — | US | disclosed |
| EP-1943254-A1 | REAGENTS FOR HIGHLY SPECIFIC DETECTION OF PEROXYNITRITE | The University of Hong Kong (CN) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007041923-A1 | REAGENTS FOR HIGHLY SPECIFIC DETECTION OF PEROXYNITRITE | THE UNIVERSITY OF HONG KONG (CN) | 2007-04-19 | — | — | WO | disclosed |
| US-20070082403-A1 | Reagents for highly specific detection of peroxynitrite | VERSITECH LIMITED (HK) | 2007-04-12 | — | — | US | disclosed |
| US-20070082403-A1 | Reagents for highly specific detection of peroxynitrite | VERSITECH LIMITED (HK) | 2007-04-12 | — | — | US | disclosed |