Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432122 | 0.88 | FFAR1 (0.42) | PPARAPPARDFFAR1FFAR2FFAR4 | |
| SCHEMBL3790720 | 0.82 | ALOX5 (0.48) | PTPN1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL2851682 | 0.80 | CYP4F2 (0.40) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL24795607 | 0.79 | ERN1 (0.38) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2257211 | 0.79 | F2RL1 (0.46) | ALDH1A1MAPTKMT2AIDO1CA12 | |
| SCHEMBL7062043 | 0.79 | CDK1 (0.41) | MAPTPPARACA9CA2CA1 | |
| SCHEMBL7220494 | 0.78 | POLB (0.39) | PTPN1PPARAPPARDIDO1CA12 | |
| SCHEMBL18232227 | 0.78 | PTPN1 (0.43) | PTPN1ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL1175106 | 0.78 | NOTUM (0.44) | ALDH1A1MAPTKDM4EKMT2ACA12 | |
| SCHEMBL18511728 | 0.78 | CA12 (0.45) | PTPN1ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022264114-A2 | ROS SENSITIVE DIAZABORINES FOR THE CONSTRUCTION OF STIMULI-RESPONSIVE BIOCONJUGATES | TECHNOPHAGE, INVESTIGAÇÃO E DESENVOLVIMENTO EM BIOTECHNOLOGIA, S.A. (PT) | 2022-12-22 | — | — | WO | disclosed |
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |
| CN-1121718-A | Heterocyclic derivatives | ZENECA LTD (GB) | 1996-05-01 | — | — | CN | disclosed |
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |