Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3790720 | 0.87 | ALOX5 (0.48) | ALDH1A1SMN1; SMN2KMT2AALOX5OR51E2 | |
| SCHEMBL4327658 | 0.86 | GAA (0.50) | CYP4F2CYP4A11ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL491276 | 0.84 | CYP4F2 (0.59) | CYP4F2CYP4A11CYP1A2LMNASMN1; SMN2 | |
| SCHEMBL8984891 | 0.83 | CYP4F2 (0.58) | CYP4F2CYP4A11CYP4Z1PDE3BPDE3A | |
| SCHEMBL2632416 | 0.83 | CYP4F2 (0.58) | CYP4F2CYP4A11ALDH1A1CYP4Z1PDE3B | |
| SCHEMBL5955075 | 0.82 | LTA4H (0.53) | CYP4F2CYP4A11CYP1A2CYP2C19LTA4H | |
| SCHEMBL491225 | 0.82 | CYP19A1 (0.60) | CYP4F2CYP4A11CYP1A2CYP2C19LMNA | |
| SCHEMBL2432179 | 0.82 | CYP4F2 (0.56) | CYP4F2CYP4A11CYP4Z1PDE3BPDE3A | |
| SCHEMBL4450867 | 0.81 | CYP4F2 (0.55) | CYP4F2CYP4A11ALDH1A1CYP4Z1LMNA | |
| SCHEMBL5685284 | 0.81 | CALM1 (0.57) | CYP4F2CYP4A11ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103965173-A | Compounds and methods for treating estrogen receptor-related disorders | HENOGEN PHARMA GROUP LTD | 2014-08-06 | — | — | CN | disclosed |
| CN-103965172-A | Compounds and methods for treating estrogen receptor-related disorders | SHENOGEN PHARMA GROUP LTD | 2014-08-06 | — | — | CN | disclosed |
| CN-103755673-A | Compounds and methods for treating estrogen receptor-related disorders | SHENOGEN PHARMA GROUP LTD | 2014-04-30 | — | — | CN | disclosed |