Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 13/20 | 1.00 |
| ▸ | F2 | P00734 | 11/20 | 1.00 |
| ▸ | PRSS1 | P07477 | 8/20 | 1.00 |
| ▸ | PRSS2 | P07478 | 8/20 | 1.00 |
| ▸ | PRSS3 | P35030 | 8/20 | 1.00 |
| ▸ | PLAU | P00749 | 1/20 | 0.68 |
| ▸ | F10 | P00742 | 1/20 | 0.66 |
| ▸ | FURIN | P09958 | 1/20 | 0.66 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.62 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.62 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.62 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.62 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.62 |
| ▸ | PLG | P00747 | 3/20 | 0.59 |
| ▸ | TNKS | O95271 | 1/20 | 0.57 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.57 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789265 | 0.89 | ST14 (0.83) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3793330 | 0.83 | ST14 (0.71) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL483100 | 0.82 | ST14 (1.00) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL17084494 | 0.82 | ST14 (1.00) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL851834 | 0.81 | ST14 (1.00) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3803040 | 0.80 | ST14 (0.64) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6579180 | 0.79 | F2 (1.00) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1718819 | 0.79 | PARP10 (0.71) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8514698 | 0.79 | ST14 (0.64) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3137816 | 0.78 | PARP10 (1.00) | ST14F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140200225-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2014-07-17 | — | — | US | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200225-A1 | PROTEASE INHIBITORS | SERPINB1, TMPRSS15, PRSS1 | ST14 216/4885F2 112/4885PRSS1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.