4-Chloro-Benzoic Acid

4-Chloro-Benzoic Acid

SCHEMBL379138

O=C([O-])c1ccc(Cl)cc1.O=C([O-])c1ccc(Cl)cc1.[Zn+2]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 12/20 0.95
CA1 P00915 11/20 0.95
CES2 O00748 2/20 0.59
CES1 P23141 2/20 0.59
ALOX15 P16050 1/20 0.56
TSHR P16473 1/20 0.56
SRD5A2 P31213 1/20 0.50
GSK3B P49841 1/20 0.50
MAPK1 P28482 1/20 0.50
CA4 P22748 1/20 0.50
ERCC5 P28715 1/20 0.48
FEN1 P39748 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Chloro-Benzoic Acid SCHEMBL9316882 0.95 CA2 (0.95) CA2CA1CES2CES1ALOX15
4-Chloro-Benzoic Acid SCHEMBL10603885 0.95 CA2 (0.95) CA2CA1CES2CES1ALOX15
4-Chloro-Benzoic Acid SCHEMBL11173039 0.95 CA2 (0.95) CA2CA1CES2CES1ALOX15
4-Chloro-Benzoic Acid SCHEMBL9493322 0.95 CA2 (0.95) CA2CA1CES2CES1ALOX15
4-Chloro-Benzoic Acid SCHEMBL9316878 0.95 CA2 (0.95) CA2CA1CES2CES1ALOX15
4-Chloro-Benzoic Acid SCHEMBL2918289 0.95 CA2 (0.95) CA2CA1CES2CES1ALOX15
4-Chloro-Benzoic Acid SCHEMBL9149742 0.95 CA2 (0.95) CA2CA1CES2CES1ALOX15
4-Chloro-Benzoic Acid SCHEMBL8024002 0.95 CA2 (1.00) CA2CA1CES2CES1ALOX15
4-Chloro-Benzoic Acid SCHEMBL2918296 0.95 CA2 (0.95) CA2CA1CES2CES1ALOX15
4-Chloro-Benzoic Acid SCHEMBL11710684 0.95 CA2 (0.95) CA2CA1CES2CES1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110650944-B Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines 科思创德国股份有限公司 2022-07-19 CN claimed
CN-110650944-A Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines 科思创德国股份有限公司 2020-01-03 CN claimed
EP-0189760-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1989-07-19 EP claimed
US-4721701-A Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1988-01-26 US claimed
EP-0189760-A1 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1986-08-06 EP claimed
CN-110650944-B Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines 科思创德国股份有限公司 2022-07-19 CN disclosed
EP-3625210-B1 SILICA-BASED ZINC CATALYSTS. THEIR PREPARATION AND USE IN THE ALKOXYCARBONYLATION OF AMINES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2021-06-23 EP disclosed
CN-105229015-B Zinc cluster compounds and their use as catalysts in the reaction of amines with dialkyl carbonates 科思创德国股份公司 2020-11-03 CN disclosed
US-10807084-B2 Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines COVESTRO DEUTSCHLAND AG (DE) 2020-10-20 US disclosed
US-20200147594-A1 SILICA-BASED ZINC CATALYSTS, THEIR PREPARATION AND USE IN THE ALKOXYCARBONYLATION OF AMINES COVESTRO DEUTSCHLAND AG (DE) 2020-05-14 US disclosed
CN-110650944-A Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines 科思创德国股份有限公司 2020-01-03 CN disclosed
US-9988344-B2 Zinc cluster compounds and their use as catalysts in the reaction of amines with dialkyl carbonates COVESTRO DEUTSCHLAND AG (DE) 2018-06-05 US disclosed
WO-1999047493-A1 METHOD FOR THE PREPARATION OF ORGANIC CARBAMATES HUNTSMAN ICI CHEMICALS LLC (US) 1999-09-23 WO disclosed
WO-1998056758-A1 PROCESS FOR THE PRODUCTION OF ORGANIC ISOCYANATES HUNTSMAN ICI CHEMICALS LLC (US) 1998-12-17 WO disclosed
WO-1998055450-A1 METHOD FOR THE PREPARATION OF CARBAMATES HUNTSMAN ICI CHEMICALS LLC (US) 1998-12-10 WO disclosed
WO-1998055451-A1 METHOD FOR THE PREPARATION OF CARBAMATES HUNTSMAN ICI CHEMICALS LLC (US) 1998-12-10 WO disclosed
US-4868151-A SULFONE COLOR DEVELOPER, FLUORENE TYPE LEUCO DYE JUJO PAPER CO., LTD. (JP) 1989-09-19 US disclosed
US-4721701-A Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1988-01-26 US disclosed
EP-0065026-A1 Preparation of carbamates from aromatic amines and organic carbonates THE DOW CHEMICAL COMPANY (US) 1982-11-24 EP disclosed
US-4268683-A ZIN OR TIN COMPOUNDS AS ACID CATALYSTS THE DOW CHEMICAL COMPANY (US) 1981-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200147594-A1 SILICA-BASED ZINC CATALYSTS, THEIR PREPARATION AND USE IN THE ALKOXYCARBONYLATION OF AMINES CDYL, ZYX, CXXC4 CA2 166/4885CA1 438/4885CES2 794/4885
US-10807084-B2 Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines CDYL, ZYX, CXXC4 CA2 166/4885CA1 438/4885CES2 794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.