⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1350797 | 0.87 | PARL (0.30) | — | |
| SCHEMBL1350799 | 0.63 | PARL (0.31) | — | |
| SCHEMBL1350795 | 0.63 | PARL (0.31) | — | |
| SCHEMBL16875685 | 0.60 | CA12 (0.32) | — | |
| SCHEMBL230242 | 0.60 | — | — | |
| SCHEMBL1702307 | 0.60 | PARL (0.50) | — | |
| SCHEMBL1273849 | 0.59 | — | — | |
| SCHEMBL949638 | 0.59 | ALDH1A1 (0.35) | — | |
| SCHEMBL28981837 | 0.58 | PARL (0.48) | — | |
| SCHEMBL949639 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408470-A1 | Soluble non-depot insulin conjugates and uses thereof | Smartcells, Inc. (US) | 2012-01-25 | — | — | EP | claimed |
| WO-2010107520-A1 | SOLUBLE NON-DEPOT INSULIN CONJUGATES AND USES THEREOF | SMARTCELLS, INC. (US) | 2010-09-23 | — | — | WO | claimed |
| US-20140037699-A1 | SOLUBLE NON-DEPOT INSULIN CONJUGATES AND USES THEREOF | SMARTCELLS, INC. (US) | 2014-02-06 | — | — | US | disclosed |
| US-8569231-B2 | Soluble non-depot insulin conjugates and uses thereof | SMARTCELLS, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| EP-2408470-A1 | Soluble non-depot insulin conjugates and uses thereof | Smartcells, Inc. (US) | 2012-01-25 | — | — | EP | disclosed |
| US-20120010134-A1 | SOLUBLE NON-DEPOT INSULIN CONJUGATES AND USES THEREOF | SMARTCELLS, INC. | 2012-01-12 | — | — | US | disclosed |
| WO-2010107520-A1 | SOLUBLE NON-DEPOT INSULIN CONJUGATES AND USES THEREOF | SMARTCELLS, INC. (US) | 2010-09-23 | — | — | WO | disclosed |