Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | MPL | P40238 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 3/20 | 0.46 |
| ▸ | PDE2A | O00408 | 3/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30779699 | 0.98 | IDO1 (0.52) | ALDH1A1IDO1MPLKDM4EPKM | |
| Bromide SCHEMBL29950269 | 0.98 | ALDH1A1 (0.50) | ALDH1A1IDO1MPLKDM4EPKM | |
| SCHEMBL3899696 | 0.83 | KIF11 (0.57) | ALDH1A1KIF11 | |
| SCHEMBL5366083 | 0.82 | ALDH1A1 (0.48) | ALDH1A1IDO1MPLKDM4EPKM | |
| SCHEMBL941310 | 0.82 | ALDH1A1 (0.48) | ALDH1A1IDO1MPLKDM4EPKM | |
| SCHEMBL9727879 | 0.82 | ALDH1A1 (0.48) | ALDH1A1IDO1MPLKDM4EPKM | |
| SCHEMBL309479 | 0.81 | ALDH1A1 (0.52) | ALDH1A1IDO1MPLKDM4EPKM | |
| SCHEMBL161784 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL29505675 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL4381686 | 0.79 | IDO1 (0.52) | ALDH1A1IDO1MPLKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 419 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800848-A | Method for synthesizing 2-fluoro-4- (trifluoromethyl) aniline | 苏州莱克施德药业有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117712391-A | Electrode catalyst, preparation method thereof, membrane electrode and fuel cell | 苏州擎动动力科技有限公司 | 2024-03-15 | — | — | CN | claimed |
| EP-2906559-B1 | AZAINDOLINES | HOFFMANN LA ROCHE (CH) | 2017-02-08 | — | — | EP | claimed |
| US-9309248-B2 | Azaindolines | HOFFMANN-LA ROCHE INC. (US) | 2016-04-12 | — | — | US | claimed |
| US-20150266879-A1 | AZAINDOLINES | HOFFMANN-LA ROCHE INC. | 2015-09-24 | — | — | US | claimed |
| EP-2906559-A1 | AZAINDOLINES | F. Hoffmann-La Roche AG (CH) | 2015-08-19 | — | — | EP | claimed |
| WO-2014056871-A1 | AZAINDOLINES | F. HOFFMANN-LA ROCHE AG (CH) | 2014-04-17 | — | — | WO | claimed |
| EP-1524261-B1 | Process for preparing fluorinated anilines | SALTIGO GMBH (DE) | 2008-06-11 | — | — | EP | claimed |
| US-7154006-B2 | Preparation of fluorinated anilines | BAYER AKTIENGESELLSCHAFT (DE) | 2006-12-26 | — | — | US | claimed |
| US-20050101795-A1 | Preparation of fluorinated anilines | BAYER CHEMICALS AG | 2005-05-12 | — | — | US | claimed |
| EP-1524261-A1 | Process for preparing fluorinated anilines | Bayer Chemicals AG (DE) | 2005-04-20 | — | — | EP | claimed |
| EP-0543633-B1 | Process for producing 4-amino-3-fluorobenzotrifluoride | SUMITOMO CHEMICAL CO (JP) | 1996-10-30 | — | — | EP | claimed |
| US-5300692-A | Process for producing 4-amino-3-fluorobenzotrifluoride | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-04-05 | — | — | US | claimed |
| EP-0543633-A2 | Process for producing 4-amino-3-fluorobenzotrifluoride | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-26 | — | — | EP | claimed |
| US-4766243-A | Electrophilic fluorination of aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1988-08-23 | — | — | US | claimed |
| JP-5201935-A | — | — | None | — | — | JP | disclosed |
| EP-4347571-B1 | TRIAZINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER. | HOFFMANN LA ROCHE (CH) | 2026-04-22 | — | — | EP | disclosed |
| US-4243819-A | Substituted amino acids | ZOECON CORPORATION (US) | 1981-01-06 | — | — | US | disclosed |
| US-4226802-A | 2-(4-Trifluoromethylphenylamino)-3-methylbutanoic acid esters and intermediates therefor | ZOECON CORPORATION (US) | 1980-10-07 | — | — | US | disclosed |
| US-4059402-A | SUBLIMATION, MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101795-A1 | Preparation of fluorinated anilines | FLNA, FLNB, FLI1 | ALDH1A1 559/4885IDO1 721/4885MPL 2497/4885 |
| US-20150266879-A1 | AZAINDOLINES | AZI2, H1-5, CCNY | ALDH1A1 682/4885IDO1 449/4885MPL 1916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.