Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718144 | 0.74 | MGLL (0.41) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL8471148 | 0.69 | — | — | |
| SCHEMBL23045146 | 0.69 | DDAH1 (0.33) | MGLLGSK3AGSK3B | |
| SCHEMBL30787946 | 0.67 | GSK3A (0.31) | GSK3AGSK3BALDH1A1LMNAMAPT | |
| SCHEMBL723636 | 0.67 | — | — | |
| SCHEMBL379177 | 0.66 | MGLL (0.39) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL10606609 | 0.64 | — | — | |
| SCHEMBL157324 | 0.58 | MGLL (0.50) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL25413969 | 0.58 | MGLL (0.33) | MGLLGSK3AGSK3BFAAHNPSR1 | |
| SCHEMBL4857568 | 0.57 | MGLL (0.41) | MGLLGSK3AGSK3BFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090214438-A1 | METHODS AND COMPOSITIONS FOR THE PREPARATION AND USE OF TOXIN CONJUGATES | INSTITUT CURIE (FR) | 2009-08-27 | — | — | US | disclosed |
| WO-2009077586-A2 | METHODS AND COMPOSITIONS FOR THE PREPARATION AND USE OF TOXIN CONJUGATES | INSTITUT CURIE (FR) | 2009-06-25 | — | — | WO | disclosed |
| EP-2072060-A1 | Methods and compositions for the preparation and use of toxin conjugates. | Institut Curie (FR) | 2009-06-24 | — | — | EP | disclosed |