Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17818683 | 0.97 | CYP1A2 (0.31) | CYP1A2CYP2D6MAPTCYP2C9CYP2C19 | |
| SCHEMBL16419664 | 0.85 | ALDH1A1 (0.39) | CYP1A2CYP2D6MAPTCYP2C9CYP2C19 | |
| SCHEMBL23856676 | 0.84 | — | — | |
| SCHEMBL16418483 | 0.78 | CYP2C19 (0.37) | CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL25362363 | 0.75 | — | — | |
| SCHEMBL1027710 | 0.74 | — | — | |
| SCHEMBL3047206 | 0.72 | — | — | |
| Silver SCHEMBL17818682 | 0.72 | BBOX1 (0.32) | — | |
| SCHEMBL29134071 | 0.72 | — | — | |
| SCHEMBL9747384 | 0.72 | TSHR (0.36) | CYP1A2CYP2D6MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025102171-A1 | COMBUSTIBLE CONTAINERS MANUFACTURED USING REACTIVE INJECTION MOLDING OF AZIDO POLYMERS | GENERAL DYNAMICS ORDNANCE AND TACTICAL SYSTEMS - CANADA, INC. (CA) | 2025-05-22 | — | — | WO | disclosed |
| US-20240190880-A1 | SMALL MOLECULE DEGRADERS OF ESTROGEN RECEPTOR WITH CEREBLON LIGANDS | REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-06-13 | — | — | US | disclosed |
| US-20240150360-A1 | Small Molecule Degraders of CBP/p300 Proteins | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-05-09 | — | — | US | disclosed |
| US-20230357249-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS WITH A TRICYCLIC CEREBLON LIGAND | UNIV MICHIGAN REGENTS (US) | 2023-11-09 | — | — | US | disclosed |
| EP-4208500-A1 | POLYMERS CONTAINING REPEATING UNITS WITH SEVERAL METAL OR ORGANIC SULPHONATE UNITS, METHODS FOR PREPARING SAME AND USES THEREOF | CDP-Innovation (FR) | 2023-07-12 | — | — | EP | disclosed |
| US-20220388978-A1 | CEREBLON E3 LIGASE INHIBITORS | REGENTS OF THE UNIVERSITY OF MICHIGAN | 2022-12-08 | — | — | US | disclosed |
| EP-4021580-A1 | CEREBLON E3 LIGASE INHIBITORS | The Regents Of The University Of Michigan (US) | 2022-07-06 | — | — | EP | disclosed |
| WO-2022049236-A1 | POLYMERS CONTAINING REPEATING UNITS WITH SEVERAL METAL OR ORGANIC SULPHONATE UNITS, METHODS FOR PREPARING SAME AND USES THEREOF | CDP INNOVATION (FR) | 2022-03-10 | — | — | WO | disclosed |
| WO-2021231927-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS WITH A TRICYCLIC CEREBLON LIGAND | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-11-18 | — | — | WO | disclosed |
| WO-2021055756-A1 | SPIROCYCLIC ANDROGEN RECEPTOR PROTEIN DEGRADERS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-03-25 | — | — | WO | disclosed |
| WO-2010088286-A1 | SYNTHETIC CONJUGATES AND USES THEREOF | SMARTCELLS, INC. (US) | 2010-08-05 | — | — | WO | disclosed |
| CN-100448841-C | Process for preparing 2-cyclohexenone compounds | UNIV ZHEJIANG (CN) | 2009-01-07 | — | — | CN | disclosed |
| CN-101104587-A | 2-cyclohexenone compounds | UNIV ZHEJIANG (CN) | 2008-01-16 | — | — | CN | disclosed |
| CN-100358857-C | 2-cyclohexenone compounds and preparation method thereof | UNIV ZHEJIANG (CN) | 2008-01-02 | — | — | CN | disclosed |
| CN-1951903-A | Process for preparing 2-cyclohexenone compounds | UNIV ZHEJIANG (CN) | 2007-04-25 | — | — | CN | disclosed |
| CN-1827577-A | 2-cyclohexenone compounds and preparation method thereof | UNIV ZHEJIANG (CN) | 2006-09-06 | — | — | CN | disclosed |
| EP-0807101-B1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | UPJOHN CO (US) | 2001-06-13 | — | — | EP | disclosed |
| US-5936000-A | 2-aminoindans as selective dopamine D3 ligands | PHARMACIA & UPJOHN COMPANY (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0807101-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996023760-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357249-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS WITH A TRICYCLIC CEREBLON LIGAND | AR, GPER1, CRBN | CYP1A2 169/4885CYP2D6 568/4885MAPT 3146/4885 |
| US-20240150360-A1 | Small Molecule Degraders of CBP/p300 Proteins | EP300, CREBBP, NCOR1 | CYP1A2 3688/4885CYP2D6 3390/4885MAPT 1498/4885 |
| US-20240190880-A1 | SMALL MOLECULE DEGRADERS OF ESTROGEN RECEPTOR WITH CEREBLON LIGANDS | ESR1, CRBN, ESR2 | CYP1A2 661/4885CYP2D6 672/4885MAPT 3618/4885 |
| US-20220388978-A1 | CEREBLON E3 LIGASE INHIBITORS | CRBN, CUL3, UBE3A | CYP1A2 3810/4885CYP2D6 4059/4885MAPT 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.