Isobutyramide

Isobutyramide

SCHEMBL3793441

CC#N.CC(C)C(N)=O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isobutyramide SCHEMBL2357147 0.87
Isobutyramide SCHEMBL2548633 0.87
Isobutyramide SCHEMBL7569768 0.87 LMNA (0.43)
Isobutyramide SCHEMBL23363968 0.83 MCL1 (0.31)
Isobutyramide SCHEMBL27949096 0.83
Isobutyramide SCHEMBL2829019 0.83
Isobutyramide SCHEMBL3323 0.83
Isobutyramide SCHEMBL11109750 0.83 LMNA (0.46)
Isobutyramide SCHEMBL11385303 0.80 ALDH1A1 (0.47)
Isobutyramide SCHEMBL2402176 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080312430-A1 Method of Preparing or Synthesizing Polyazamacrocycle Derivatives THERAPHARM GMBH (CH) 2008-12-18 US claimed
EP-1812453-A1 METHOD OF PREPARING OR SYNTHESIZING POLYAZAMACROCYCLE DERIVATIVES Therapharm GmbH (CH) 2007-08-01 EP claimed
WO-2006045546-A1 METHOD OF PREPARING OR SYNTHESIZING POLYAZAMACROCYCLE DERIVATIVES THERAPHARM GMBH (CH) 2006-05-04 WO claimed
US-4000139-A ERGOT ALKALOID INTERMEDIATES SANDOZ LTD. (CH) 1976-12-28 US claimed
US-20200339622-A1 METHOD FOR PREPARING A FARNESOID X RECEPTOR AGONIST DIPHARMA FRANCIS S.R.L. (IT) 2020-10-29 US disclosed
US-10752654-B2 Method for preparing a farnesoid X receptor agonist DIPHARMA FRANCIS S.R.L. (IT) 2020-08-25 US disclosed
US-20190106455-A1 METHOD FOR PREPARING A FARNESOID X RECEPTOR AGONIST DIPHARMA FRANCIS S.R.L. (IT) 2019-04-11 US disclosed
EP-3440092-A1 METHOD FOR PREPARING A FARNESOID X RECEPTOR AGONIST Dipharma Francis S.r.l. (IT) 2019-02-13 EP disclosed
CN-105246940-B Optical semiconductor sealing solidification compound 株式会社大赛璐 2018-09-04 CN disclosed
CN-108353475-A composition for sealing 株式会社大赛璐 2018-07-31 CN disclosed
US-20180200378-A1 COMPOUNDS FOR TREATING CANCER Bicyclerd Limited (GB) 2018-07-19 US disclosed
CN-108043476-A The manufacturing method of the renovation process of hydrogenation catalyst and the hydride of polyalcohol 株式会社大赛璐 2018-05-18 CN disclosed
EP-0968197-A1 EFFICIENT SYNTHESIS OF A 1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE Merck & Co., Inc. (US) 2000-01-05 EP disclosed
US-5922864-A ADDING AN ARYL CHLOROFORMATE TO A STIRRING MIXTURE OF AN AMINO ALCOHOL DERIVATIVE IN AN ORGANIC SOLVENT WITH A BASE TO PRODUCE CARBAMATE INTERMEDIATE, STIRRING, QUENCHING WITH WATER OR AQUEOUS BASE, STIRRING UNTIL CYCLIZATION, ISOLATING MERCK & CO., INC. (US) 1999-07-13 US disclosed
WO-1998034928-A1 EFFICIENT SYNTHESIS OF A 1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE MERCK & CO., INC. (US) 1998-08-13 WO disclosed
EP-0015773-B1 N-(6-((ACYLAMINOACYLAMINO OR AMINOACYLAMINO)PHENYL) 1,2-DIHYDRO-2-OXONICOTINYL)PENICILLIN COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND COMPOSITIONS CONTAINING THEM WARNER-LAMBERT COMPANY (US) 1983-07-20 EP disclosed
US-4326068-A Process of preparing hexafluorothioacetone dimer ALLIED CORPORATION (US) 1982-04-20 US disclosed
US-4278681-A N-/6-//ACYLAMINOACYLAMINO OR AMINOACYLAMINO/PHENYL/-1,2-DIHYDRO-2-OXONICOTINYL/PENICILLINS WARNER-LAMBERT CO. (US) 1981-07-14 US disclosed
EP-0015773-A2 N-(6-((acylaminoacylamino or aminoacylamino)phenyl) 1,2-dihydro-2-oxonicotinyl)penicillin compounds, processes for their production and compositions containing them WARNER-LAMBERT COMPANY (US) 1980-09-17 EP disclosed
US-4209616-A BACTERICIDES HAVING ALPHA-HYDROXIMINO- OR ALPHA-ACYLOIMINOACYLAMIDO GROUPS GLAXO LABORATORIES LIMITED (GB) 1980-06-24 US disclosed