SCHEMBL379404

SCHEMBL379404

O=Cc1cc2ccccc2nn1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 5/20 0.44
MAPT P10636 3/20 0.44
HPGD P15428 3/20 0.44
GLA P06280 1/20 0.44
ACHE P22303 1/20 0.44
GAA P10253 2/20 0.40
NQO2 P16083 1/20 0.38
P2RX7 Q99572 1/20 0.36
GPR3 P46089 1/20 0.36
CCR1 P32246 1/20 0.35
CYP1A2 P05177 2/20 0.35
PDGFRB P09619 1/20 0.35
PDGFRA P16234 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
MGAM O43451 1/20 0.35
LMNA P02545 2/20 0.35
HTT P42858 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29953056 1.00 KDM4E (0.46) KDM4EALDH1A1MAPTHPGDGLA
SCHEMBL291341 0.79 KDM4E (0.50) KDM4EALDH1A1MAPTHPGDGLA
SCHEMBL5434515 0.79 KDM4E (0.46) KDM4EALDH1A1MAPTHPGDGLA
SCHEMBL31271644 0.75 PABPC1 (0.42) ALDH1A1CCR1CYP2A6
SCHEMBL20600550 0.73 CCR1 (0.31) CCR1
SCHEMBL4254515 0.73 KDM4E (0.41) KDM4EALDH1A1MAPTHPGDGLA
SCHEMBL4254514 0.73 KDM4E (0.41) KDM4EALDH1A1MAPTHPGDGLA
SCHEMBL276035 0.71 ALDH1A1 (0.50) KDM4EALDH1A1MAPTHPGDGLA
SCHEMBL30212114 0.71 MGAM (0.57) KDM4EALDH1A1MAPTHPGDGLA
SCHEMBL3660080 0.71 MGAM (0.57) KDM4EALDH1A1MAPTHPGDGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101522638-A Pyridizinone derivatives CEPHALON INC (US) 2009-09-02 CN claimed
EP-0941998-B1 3,6-ketal macrolide antibiotics PFIZER PROD INC (US) 2004-09-01 EP claimed
US-6043226-A TREATING BACTERIAL, PARASITIC AND PROTOZOAL INFECTIONS PFIZER INC. (US) 2000-03-28 US claimed
EP-0941998-A2 3,6-ketal and enol ether macrolide antibiotics Pfizer Products Inc. (US) 1999-09-15 EP claimed
CN-1219934-A Novel pyridazine compounds ASTRA PHARMA PROD (GB) 1999-06-16 CN claimed
EP-3971201-B1 CELL CULTURING SCAFFOLD MATERIAL AND CELL CULTURING CONTAINER SEKISUI CHEMICAL CO LTD (JP) 2026-01-28 EP disclosed
EP-3971200-B1 CELL CULTURING SCAFFOLDING MATERIAL AND CELL CULTURING VESSEL SEKISUI CHEMICAL CO LTD (JP) 2026-01-21 EP disclosed
US-12460167-B2 Scaffold material for cell culture and cell culture container SEKISUI CHEMICAL CO., LTD. (JP) 2025-11-04 US disclosed
US-12365860-B2 Scaffolding material for stem cell cultures and stem cell culture method using same SEKISUI CHEMICAL CO., LTD. (JP) 2025-07-22 US disclosed
US-12234485-B2 Resin film formed by scaffold material for cell culture and container for cell culture SEKISUI CHEMICAL CO., LTD. (JP) 2025-02-25 US disclosed
US-12180450-B2 Scaffolding material for stem cell cultures and stem cell culture method using same SEKISUI CHEMICAL CO., LTD. (JP) 2024-12-31 US disclosed
US-12157875-B2 Scaffolding material for cell cultures and cell culture method using same SEKISUI CHEMICAL CO., LTD. (JP) 2024-12-03 US disclosed
CN-1218472-A Pharmaceutically useful compounds ASTRA PHARMA PROD (GB) 1999-06-02 CN disclosed
US-5478937-A Chemical intermediates for antiarrhythmia agent, antilipemic agent, vasodilator and hypotensive agent BAYER AKTIENGESELLSCHAFT (DE) 1995-12-26 US disclosed
CN-1014060-B METHOD FOR PREPARAING ORTHO-AZONAPHTHALENE COMPOUND IMP CHEMICAL IND PAN AMERICAL (US) 1991-09-25 CN disclosed
CN-1009092-B The preparation method of Pyridione derivatives SMITH KLINE FRENCH LAB (GB) 1990-08-08 CN disclosed
CN-86106546-A The preparation method of Pyridione derivatives 1987-05-20 CN disclosed
CN-85107017-A Preparation three ring pyridazinones dihydro compounds and the method that contains the pharmaceutical composition of this compound 1987-04-01 CN disclosed
US-4125530-A FROM 1,1-DIHALO-3,3,3-TRIFLUOROACETONE, BASE, AMMONIA AND A CARBOXALDEHYDE MERCK & CO., INC. (US) 1978-11-14 US disclosed
US-4032522-A ANTI-GOUT, ANTI-HYPERURICEMIC MERCK & CO., INC. (US) 1977-06-28 US disclosed