Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20599429 | 0.82 | — | — | |
| SCHEMBL29953056 | 0.73 | KDM4E (0.46) | CCR1 | |
| SCHEMBL379404 | 0.73 | KDM4E (0.46) | CCR1 | |
| SCHEMBL2899971 | 0.72 | TDP1 (0.30) | — | |
| SCHEMBL9322559 | 0.69 | ACHE (0.42) | — | |
| SCHEMBL194247 | 0.68 | KDM4E (0.58) | — | |
| SCHEMBL31271644 | 0.66 | PABPC1 (0.42) | CCR1 | |
| SCHEMBL6769735 | 0.65 | ALDH1A1 (0.31) | — | |
| SCHEMBL81622 | 0.63 | — | — | |
| SCHEMBL3834527 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019000236-A1 | 3-(1H-PYRAZOL-4-YL)PYRIDINE ALLOSTERIC MODULATORS OF M4 MUSCARINIC ACETYLCHOLINE RECEPTOR | MERCK SHARP & DOHME CORP. (US) | 2019-01-03 | — | — | WO | disclosed |