SCHEMBL379409

SCHEMBL379409

CNCCc1c[nH]c2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 6/20 1.00
HTR1A P08908 3/20 1.00
KDM4E B2RXH2 2/20 1.00
ALDH1A1 P00352 1/20 1.00
HTT P42858 1/20 1.00
MC5R P33032 1/20 0.68
MC3R P41968 1/20 0.68
MC1R Q01726 1/20 0.68
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
CYP1A2 P05177 2/20 0.65
LMNA P02545 1/20 0.65
PKM P14618 1/20 0.65
TSHR P16473 1/20 0.65
CYP2C19 P33261 1/20 0.65
BLM P54132 1/20 0.65
CYP3A4 P08684 2/20 0.63
MAPT P10636 1/20 0.63
AHR P35869 1/20 0.63
GPR84 Q9NQS5 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29385251 1.00 HTR2A (1.00) HTR2AHTR1AKDM4EALDH1A1HTT
Hydrochloric Acid SCHEMBL2684408 0.98 HTR2A (0.97) HTR2AHTR1AKDM4EALDH1A1HTT
Water SCHEMBL27796022 0.97 HTR2A (0.93) HTR2AHTR1AKDM4EALDH1A1HTT
Cyanide SCHEMBL29233340 0.95 HTR2A (0.90) HTR2AHTR1AKDM4EALDH1A1HTT
SCHEMBL1248752 0.90 HTR2A (0.81) HTR2AHTR1AKDM4EALDH1A1HTT
SCHEMBL17232881 0.85 MC5R (0.83) HTR2AHTR1AKDM4EALDH1A1HTT
SCHEMBL27034106 0.85 HTR2A (0.72) HTR2AHTR1AKDM4EALDH1A1HTT
SCHEMBL7970552 0.84 MC5R (0.81) HTR2AHTR1AKDM4EALDH1A1HTT
SCHEMBL1972829 0.83 HTR2A (1.00) HTR2AHTR1AKDM4EALDH1A1HTT
SCHEMBL4985934 0.82 HTR2A (0.77) HTR2AHTR1AKDM4EALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1063 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4297723-B1 MICRONEEDLE COMPOSITIONS AND METHODS OF DELIVERY USING THE SAME BRIGHAM & WOMENS HOSPITAL INC (US) 2026-05-20 EP claimed
US-20260090957-A1 Process for making aqueous therapeutic particle having stable exterior water clustering with nanosized thickness DRESDNER JR KARL P (US) 2026-04-02 US claimed
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US claimed
EP-4618981-A1 COMBINATIONS OF MONOAMINE OXIDASE INHIBITORS AND SEROTONIN RECEPTOR AGONISTS AND THEIR THERAPEUTIC USE Remedi, Inc. (US) 2025-09-24 EP claimed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 EP claimed
CN-120195298-A Metabolic marker composition for discriminating tobacco grades, screening method and application 哈尔滨脉图精准技术有限公司 2025-06-24 CN claimed
EP-4547250-A1 METHODS AND COMPOSITIONS RELATING TO CONTROLLING PSYCHEDELIC EFFECTS WITH SEROTONIN RECEPTOR MODULATORS Terran Biosciences Inc. (US) 2025-05-07 EP claimed
US-20250129399-A1 RECOMBINANT PRODUCTION OF PSILOCIN AND RELATED COMPOUNDS NEUERA PHARMACEUTICALS INC. (CA) 2025-04-24 US claimed
CN-119614279-A Energy-saving gear lubricating oil and preparation method thereof 安徽中天石化股份有限公司 2025-03-14 CN claimed
US-20240385183-A1 METABOLIC AND MICROBIAL BIOMARKERS FOR DETECTION OF PANCREATICOBILIARY CANCERS NORTHWESTERN UNIVERSITY 2024-11-21 US claimed
US-20040110746-A1 Piperazinyl and diazapanyl benzamides and benzthioamides JANSSEN PHARMACEUTICA N.V. (BE) 2004-06-10 US claimed
WO-2004037801-A1 PIPERAZINYL AND DIAZAPANYL BENZAMIDES AND BENZTHIOAMIDES JANSSEN PHARMACEUTICA, N.V. (BE) 2004-05-06 WO claimed
US-20040087573-A1 Phenylpiperidines and phenylpyrrolidines JANSSEN PHARMACEUTICA N.V. (BE) 2004-05-06 US claimed
WO-2004037257-A1 PHENYLPIPERIDINES AND PHENYLPYRROLIDINES AS HISTAMINE H3 RECEPTOR MODULATORS JANSSEN PHARMACEUTICA, N.V. (BE) 2004-05-06 WO claimed
US-20040002604-A1 Phenylalkynes ORTHO-MCNEIL PHARMACEUTICAL, INC. 2004-01-01 US claimed
WO-2003066579-A2 NOVEL BICYCLIC HYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE AXYS PHARMACEUTICALS (US) 2003-08-14 WO claimed
US-20030144323-A1 For treatment of disorders and conditions mediated by the histamine receptor; allergies, sleep disorders, dementia ORTHO-MCNEIL PHARMACEUTICAL, INC. 2003-07-31 US claimed
WO-2003050099-A1 PHENYLALKYNES ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2003-06-19 WO claimed
EP-0251938-B1 STEREOSPECIFIC PROCESS FOR THE SYNTHESIS OF INDOLE DERIVATIVES SANOFI (FR) 1991-11-06 EP claimed
EP-0251938-A1 Stereospecific process for the synthesis of indole derivatives SANOFI (FR) 1988-01-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040087573-A1 Phenylpiperidines and phenylpyrrolidines HRH2, HNMT, HRH3 HTR2A 51/4885HTR1A 75/4885KDM4E 2587/4885
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES PDE9A, PDE3A, PDE2A HTR2A 14/4885HTR1A 9/4885KDM4E 1355/4885
US-20040110746-A1 Piperazinyl and diazapanyl benzamides and benzthioamides HRH2, HNMT, HRH3 HTR2A 338/4885HTR1A 713/4885KDM4E 1401/4885
US-20260090957-A1 Process for making aqueous therapeutic particle having stable exterior water clustering with nanosized thickness QPCT, SLC38A7, QPCTL HTR2A 2610/4885HTR1A 2572/4885KDM4E 3063/4885
US-20030144323-A1 For treatment of disorders and conditions mediated by the histamine receptor; allergies, sleep disorders, dementia HRH3, HRH2, HRH4 HTR2A 24/4885HTR1A 17/4885KDM4E 1122/4885
US-20040002604-A1 Phenylalkynes HRH2, HRH3, HNMT HTR2A 98/4885HTR1A 103/4885KDM4E 1787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.