Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 7/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712980 | 0.89 | SLC9A1 (0.56) | SLC9A1CYP1A2CYP2C19KDM4EKMT2A | |
| SCHEMBL3707944 | 0.84 | SLC9A1 (0.52) | SLC9A1CYP1A2CYP2C19KDM4EKMT2A | |
| SCHEMBL3719608 | 0.83 | SLC9A1 (0.59) | SLC9A1KDM4EKMT2ASMN1; SMN2HPGD | |
| SCHEMBL3709278 | 0.83 | SLC9A1 (0.59) | SLC9A1KDM4EKMT2AHPGDALDH1A1 | |
| SCHEMBL3710904 | 0.82 | SLC9A1 (0.56) | SLC9A1KDM4EHPGDALDH1A1 | |
| SCHEMBL3714359 | 0.82 | SLC9A1 (0.61) | SLC9A1KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL3712739 | 0.80 | MAPT (0.56) | KDM4EKMT2ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL3788349 | 0.78 | SLC9A1 (0.55) | SLC9A1KDM4ESMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL3720065 | 0.78 | SLC9A1 (0.55) | SLC9A1KDM4EKMT2ASMN1; SMN2HPGD | |
| SCHEMBL3714406 | 0.77 | SLC9A1 (0.51) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094090-A2 | SYNUCLEINOPATHIES | KATHOLLEKE UNIVERSITEIT LEUVEN (BE) | 2010-08-26 | — | — | WO | disclosed |