Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 9/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712980 | 0.87 | SLC9A1 (0.56) | SLC9A1SMN1; SMN2LMNAALDH1A1POLB | |
| SCHEMBL3707944 | 0.83 | SLC9A1 (0.52) | SLC9A1SMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL3709278 | 0.82 | SLC9A1 (0.59) | SLC9A1ALDH1A1POLBGAAMAPT | |
| SCHEMBL3711058 | 0.82 | SLC9A1 (0.53) | SLC9A1SMN1; SMN2LMNAALDH1A1POLB | |
| SCHEMBL3710904 | 0.80 | SLC9A1 (0.56) | SLC9A1LMNAALDH1A1HPGDKDM4E | |
| SCHEMBL3709712 | 0.79 | SLC9A1 (0.56) | SLC9A1SMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL3716474 | 0.79 | SLC9A1 (0.55) | SLC9A1LMNAALDH1A1POLBMAPT | |
| SCHEMBL3783985 | 0.79 | SLC9A1 (0.55) | SLC9A1LMNAALDH1A1HPGDNQO2 | |
| SCHEMBL3795202 | 0.78 | SLC9A1 (0.61) | SLC9A1SMN1; SMN2ALDH1A1HPGDTDP1 | |
| SCHEMBL3719309 | 0.77 | SLC9A1 (0.57) | SLC9A1ALDH1A1MAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094090-A2 | SYNUCLEINOPATHIES | KATHOLLEKE UNIVERSITEIT LEUVEN (BE) | 2010-08-26 | — | — | WO | disclosed |