SCHEMBL37955

SCHEMBL37955

Cc1ccc(C)c(C)c1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.45
CYP1A2 P05177 3/20 0.45
CYP2A6 P11509 2/20 0.45
TDP2 O95551 1/20 0.45
NSD2 O96028 1/20 0.45
HSP90AA1 P07900 1/20 0.45
PAX8 Q06710 1/20 0.45
ACHE P22303 2/20 0.43
POLB P06746 1/20 0.42
TRPA1 O75762 1/20 0.42
ATM Q13315 1/20 0.42
TDP1 Q9NUW8 2/20 0.39
NOS3 P29474 2/20 0.38
NOS2 P35228 2/20 0.38
ALDH1A1 P00352 3/20 0.37
CASP1 P29466 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5494672 1.00 TSHR (0.45) TSHRCYP1A2CYP2A6TDP2NSD2
SCHEMBL5181689 0.95 TSHR (0.43) TSHRCYP1A2CYP2A6TDP2NSD2
SCHEMBL10346182 0.95 TSHR (0.43) TSHRCYP1A2CYP2A6TDP2NSD2
SCHEMBL571577 0.95 TSHR (0.43) TSHRCYP1A2CYP2A6TDP2NSD2
SCHEMBL4699685 0.88 ALDH1A1 (0.45) TSHRCYP1A2CYP2A6TDP2NSD2
SCHEMBL23854312 0.84 POLB (0.55) TSHRCYP1A2CYP2A6TDP2NSD2
SCHEMBL4078654 0.84 TSHR (0.38) TSHRCYP1A2CYP2A6TDP2NSD2
SCHEMBL4071459 0.84 TRPA1 (0.55) TSHRCYP1A2CYP2A6ACHETRPA1
SCHEMBL31673873 0.84 POLB (0.55) TSHRCYP1A2CYP2A6TDP2NSD2
Ethylenediamine SCHEMBL18725865 0.82 TAAR1 (0.42) TSHRCYP1A2CYP2A6TDP2NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12578 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146709-B Double-component polyurethane varnish, preparation method thereof, paint layer and paint layer product HUNAN XIANGJIANG KANSAI PAINT(CHANGSHA) Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122059921-A Preparation method of vinyl sulfate 大连理工大学 2026-05-19 CN claimed
CN-122060475-A High-carbon-number paraffin wax remover and evaluation method thereof 中国石油天然气股份有限公司 2026-05-19 CN claimed
CN-122036532-A Asphaltene dispersants and methods of making same 中国石油管道局工程有限公司 2026-05-15 CN claimed
CN-122036713-A Quinoline derivative compound and preparation method and application thereof 东北农业大学 2026-05-15 CN claimed
CN-122004231-A Comprising an oxa carfentrazone-ethyl herbicide composition and application thereof 山东滨农科技有限公司 2026-05-12 CN claimed
CN-122004230-A Comprising an oxa carfentrazone-ethyl herbicide composition and application thereof 山东滨农科技有限公司 2026-05-12 CN claimed
US-12624231-B2 Organic solvent composition and paint composition comprising the same ANAME OF ASSIGNEE Innovation Co., Ltd. (KR) 2026-05-12 US claimed
EP-4072992-B1 COMPOSITION SAMSUNG ELECTRONICS CO LTD (KR) 2026-04-08 EP claimed
US-20260055038-A1 SLURRY CONTAINING AN AROMATIC HYDROCARBON AND METHODS THEREOF SOLID POWER OPERATING INC (US) 2026-02-26 US claimed
US-4070364-A Process for the production of [2-acetoacetyl-aminothiazolyl-(4)-]-acetic acid ethyl ester LONZA, LTD. (CH) 1978-01-24 US claimed
US-4038335-A METHOD OF PREPARING BENZENE AND METHYLBENZENES MINACHEV KHABIB MINACHEVICH 1977-07-26 US claimed
US-4024170-A Liquid clathrates THE UNIVERSITY OF ALABAMA (US) 1977-05-17 US claimed
US-4000120-A POLYETHYLENE, POLYPROPYLENE, POLYSTYRENE SNAM PROGETTI S.P.A. (IT) 1976-12-28 US claimed
US-3998886-A PRODUCTION OF HALOGEN-CONTAINING TERTIARY PHOSPHINE OXIDES HOECHST AKTIENGESELLSCHAFT (DT) 1976-12-21 US claimed
US-3962363-A REACTING TOLUENE, METHANOL, AND A POLYMETHYLBENZENE, ACID CATALYST INSTITUT FRANCAIS DU PETROLE DES CARBURANTS ET LUBRIFIANTS (FR) 1976-06-08 US claimed
US-3952037-A Aluminum catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-04-20 US claimed
US-3936307-A Light and heat sensitive composition for producing a colored transfer complex image MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) 1976-02-03 US claimed
US-3933752-A COPOLYMERIZATION USING ARENE-METAL TRICARBONYL FRIEDEL-CRAFTS CATALYSTS THE UNIVERSITY OF AKRON (US) 1976-01-20 US claimed
US-3931333-A HYDROGEN CHLORIDE HOECHST AKTIENGESELLSCHAFT (DT) 1976-01-06 US claimed