Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.32 |
| ▸ | ITGAL | P20701 | 2/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3795534 | 1.00 | ELANE (0.34) | ELANENR3C1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL3015521 | 0.94 | KDM4E (0.32) | ELANENR3C1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL3022092 | 0.93 | PGR (0.32) | ELANENR3C1GRIA2GRIA4HTR7 | |
| SCHEMBL3800289 | 0.93 | ITGB2 (0.33) | ELANENR3C1ITGB2ICAM1ITGAL | |
| SCHEMBL3800288 | 0.93 | ITGB2 (0.33) | ELANENR3C1ITGB2ICAM1ITGAL | |
| SCHEMBL3022091 | 0.93 | PGR (0.32) | ELANENR3C1GRIA2GRIA4HTR7 | |
| SCHEMBL3795466 | 0.92 | RIPK1 (0.31) | ELANEGRIA2GRIA4 | |
| SCHEMBL3795469 | 0.92 | RIPK1 (0.31) | ELANEGRIA2GRIA4 | |
| SCHEMBL3029255 | 0.91 | PKM (0.36) | SMN1; SMN2ALDH1A1TSHRHSD17B10GRIA2 | |
| SCHEMBL3029253 | 0.91 | PKM (0.36) | SMN1; SMN2ALDH1A1TSHRHSD17B10GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152047-A1 | Piperazine Compounds Whith a Herbicidal Action | BASF SE (DE) | 2010-06-17 | — | — | US | claimed |
| US-20100152047-A1 | Piperazine Compounds Whith a Herbicidal Action | BASF SE (DE) | 2010-06-17 | — | — | US | disclosed |
| EP-2054395-A2 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | Basf Se (DE) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008152073-A2 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2008-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152047-A1 | Piperazine Compounds Whith a Herbicidal Action | CBR3, CBR1, CNPY2 | ELANE 3135/4885NR3C1 273/4885KDM4E 4015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.