Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 9/20 | 0.59 |
| ▸ | THRB | P10828 | 9/20 | 0.59 |
| ▸ | RARB | P10826 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | RARA | P10276 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.55 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12040863 | 1.00 | THRA (0.59) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL6123675 | 1.00 | THRA (0.59) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL11393726 | 1.00 | THRA (0.59) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL6899814 | 1.00 | THRA (0.59) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL6900234 | 1.00 | THRA (0.59) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL570964 | 0.98 | RARB (0.58) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL11043289 | 0.95 | RARB (0.68) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL4182052 | 0.95 | RARB (0.68) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL570747 | 0.93 | ESR1 (0.59) | THRATHRBRARBALDH1A1CA12 | |
| SCHEMBL21656965 | 0.93 | THRB (0.52) | THRATHRBRARBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10597391-B2 | Urea-containing isoxazole derivatives as FXR agonists and methods of use thereof | ENANTA PHARMACEUTICALS, INC. (US) | 2020-03-24 | — | — | US | disclosed |
| US-20180141941-A1 | UREA-CONTAINING ISOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. | 2018-05-24 | — | — | US | disclosed |
| US-7692187-B2 | Organic semiconductor material and organic device using the same | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2010-04-06 | — | — | US | disclosed |
| US-20070215872-A1 | Organic semiconductor material and organic device using the same | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY | 2007-09-20 | — | — | US | disclosed |
| US-6007739-A | FOR DISPLAY OF A CLOCK, A CALCULATOR, A WORD PROCESSOR, A SMALL TV SET; CAN BE DRIVEN AT A HIGH SPEED AT A LOW VOLTAGE | SHARP KABUSHIKI KAISHA (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0632116-B1 | A smectic C liquid crystal composition and a liquid crystal display element | CHISSO CORP (JP) | 1999-09-08 | — | — | EP | disclosed |
| US-5658492-A | POSITIONING LIQUID CRYSTAL BETWEEN THE PAIR OF INSULATING SUBSTRATE, EACH HAVING AN ELECTRODE, SELECTIVELY IMPRESSING A VOLTAGE ONTO SAID ELECTRODE | CHISSO CORPORATION (JP) | 1997-08-19 | — | — | US | disclosed |
| US-5529717-A | CONTAINING DIPHENYLTHIADIAZOLE AND ALKOXYPHENYLPYRIDINE COMPOUNDS | CHISSO CORPORATION (JP) | 1996-06-25 | — | — | US | disclosed |
| US-4507450-A | COORDINATION CATALYSTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1985-03-26 | — | — | US | disclosed |
| US-4229558-A | HAVING HIGH ISOTACTIC INDEX BY USING A CATALYST PREPARED FROM A MAGNESIUM GRIGNARD REAGENT, TITANIUM HALIDE AN ETHER AND A CARBOXYLIC ESTER COMBINED WITH AN ORGANOALUMINUM COMPOUND | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1980-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141941-A1 | UREA-CONTAINING ISOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF | NR1H4, FXR1, SLC10A1 | THRA 468/4885THRB 461/4885RARB 877/4885 |
| US-10597391-B2 | Urea-containing isoxazole derivatives as FXR agonists and methods of use thereof | NR1H4, FXR1, SLC10A1 | THRA 468/4885THRB 461/4885RARB 877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.