Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 4/20 | 0.45 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.44 |
| ▸ | ITGAL | P20701 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chromanone SCHEMBL28794 | 0.88 | MAOB (0.56) | MAOBMAOAPKMTSHRCYP2A6 | |
| Chromanone SCHEMBL28205525 | 0.88 | MAOB (0.56) | MAOBMAOAPKMTSHRCYP2A6 | |
| Chromanone SCHEMBL29384996 | 0.88 | MAOB (0.56) | MAOBMAOAPKMTSHRCYP2A6 | |
| Chromanone SCHEMBL28719460 | 0.86 | MAOB (0.55) | MAOBMAOAPKMTSHRCYP2A6 | |
| Chromanone SCHEMBL27846233 | 0.86 | MAOB (0.55) | MAOBMAOAPKMTSHRCYP2A6 | |
| Chromanone SCHEMBL28463260 | 0.86 | MAOB (0.55) | MAOBMAOAPKMTSHRCYP2A6 | |
| Chromanone SCHEMBL30017864 | 0.86 | MAOB (0.55) | MAOBMAOAPKMTSHRCYP2A6 | |
| Chromanone SCHEMBL7617916 | 0.86 | MAOB (0.55) | MAOBMAOAPKMTSHRCYP2A6 | |
| Chromanone SCHEMBL29349977 | 0.86 | MAOB (0.55) | MAOBMAOAPKMTSHRCYP2A6 | |
| Chromanone SCHEMBL28145031 | 0.84 | MAOB (0.53) | MAOBMAOAPKMTSHRGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111518117-B | 1, 2-oxazinopyran compound and preparation method and application thereof | 西安凯新生物科技有限公司 | 2022-08-26 | — | — | CN | claimed |
| CN-111518117-A | 1, 2-oxazinopyran compound and preparation method and application thereof | 朱翠萍 | 2020-08-11 | — | — | CN | claimed |
| US-20050282863-A1 | Novel-N substituted dihydrobenzothiepino, dihydrobenzoxepino and tetrahydro benzocyclohepta indoles as selective estrogen receptor modulators | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-12-22 | — | — | US | claimed |
| WO-2005094833-A1 | NOVEL N-SUBSTITUTED DIHYDROBENZOTHIEPINO, DIHYDROBENZOXEPINO AND TETRAHYDRO BENZOCYCLOHEPTA INDOLES AS SELECTIVE ESTROGEN RECEPTOR MODULATORS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-10-13 | — | — | WO | claimed |
| WO-2001000775-A1 | BENZOLACTONES AS BLEACH ACTIVATORS | U.S. BORAX INC. (US) | 2001-01-04 | — | — | WO | claimed |
| EP-0024560-B1 | 3-AMINO-1-BENZOXEPINE DERIVATIVES AND THEIR SALTS, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Kali-Chemie Pharma GmbH (DE) | 1983-04-13 | — | — | EP | claimed |
| US-4279904-A | GASTROINTESTINAL DISORDERS | KALI-CHEMIE PHARMA GMBH (DE) | 1981-07-21 | — | — | US | claimed |
| EP-0024560-A1 | 3-Amino-1-benzoxepine derivatives and their salts, processes for their preparation and medicaments containing them | Kali-Chemie Pharma GmbH (DE) | 1981-03-11 | — | — | EP | claimed |
| US-20260085073-A1 | PYRAZOLYLCARBOXAMIDE COMPOUNDS AND THEIR USE IN THERAPY | HOTSPOT THERAPEUTICS INC (US) | 2026-03-26 | — | — | US | disclosed |
| US-12565488-B2 | Inhibitors of influenza virus replication | COCRYSTAL PHARMA, INC. (US) | 2026-03-03 | — | — | US | disclosed |
| US-11725001-B2 | Bicyclic compound and use thereof | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2023-08-15 | — | — | US | disclosed |
| WO-2023026884-A1 | CURABLE COMPOSITION, METHOD FOR PRODUCING CURED PRODUCT, FILM, OPTICAL ELEMENT, IMAGE SENSOR, SOLID STATE IMAGE SENSOR, IMAGE DISPLAY DEVICE, AND RADICAL POLYMERIZATION INITIATOR | 富士フイルム株式会社 | 2023-03-02 | — | — | WO | disclosed |
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |
| CN-111518117-B | 1, 2-oxazinopyran compound and preparation method and application thereof | 西安凯新生物科技有限公司 | 2022-08-26 | — | — | CN | disclosed |
| US-4766212-A | ANALGESICS, MUSCLE RELAXANTS, HYPOTENSIVE AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0116373-B1 | 2H-(1) BENZOXEPINO(5,4-B)-1,4-OXAZINE DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-04-15 | — | — | EP | disclosed |
| EP-0116372-B1 | 2H-(1) BENZOXEPINO (5,4-B)-1,4 OXAZINE DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-01-21 | — | — | EP | disclosed |
| EP-0116372-A1 | 2H-(1) benzoxepino (5,4-b)-1,4 oxazine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-08-22 | — | — | EP | disclosed |
| EP-0116373-A1 | 2H-(1) benzoxepino(5,4-b)-1,4-oxazine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-08-22 | — | — | EP | disclosed |
| US-4179516-A | Ethers of 3,4-dihydro-1-benzoxepin-5-one oxime to treat intestinal disorders | ALBERT ROLLAND, S.A. (FR) | 1979-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282863-A1 | Novel-N substituted dihydrobenzothiepino, dihydrobenzoxepino and tetrahydro benzocyclohepta indoles as selective estrogen receptor modulators | ESR1, ESR2, HSD17B11 | MAOB 256/4885MAOA 369/4885PKM 3826/4885 |
| US-12565488-B2 | Inhibitors of influenza virus replication | IFNAR1, HCFC1, NR3C1 | MAOB 1299/4885MAOA 1335/4885PKM 4832/4885 |
| US-11725001-B2 | Bicyclic compound and use thereof | PRMT5, PRMT6, PRMT1 | MAOB 3338/4885MAOA 3468/4885PKM 777/4885 |
| US-20260085073-A1 | PYRAZOLYLCARBOXAMIDE COMPOUNDS AND THEIR USE IN THERAPY | MALT1, BCL6, BCL3 | MAOB 4757/4885MAOA 4734/4885PKM 3785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.