SCHEMBL379634

SCHEMBL379634

Nc1ccc(-c2c(-c3ccc(CO)cc3)c(-c3ccc(CO)cc3)c(N)c(-c3ccc(CO)cc3)c2-c2ccc(CO)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.41
TDP1 Q9NUW8 3/20 0.41
ALDH1A1 P00352 2/20 0.41
TSHR P16473 2/20 0.41
GFER P55789 1/20 0.41
TP53 P04637 1/20 0.40
LOXL2 Q9Y4K0 1/20 0.39
CYP17A1 P05093 1/20 0.38
CYP19A1 P11511 1/20 0.38
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
CA14 Q9ULX7 2/20 0.36
CA4 P22748 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1309905 0.84 CYP3A4 (0.58) CYP3A4TDP1ALDH1A1TSHRGFER
SCHEMBL54121 0.82
SCHEMBL9330651 0.82 CYP3A4 (0.59) CYP3A4TDP1ALDH1A1TSHRGFER
SCHEMBL28175406 0.81 LOXL2 (0.65) CYP3A4TDP1ALDH1A1TSHRGFER
SCHEMBL9821744 0.79 CYP3A4 (0.56) CYP3A4TDP1ALDH1A1TSHRGFER
Hydrochloric Acid SCHEMBL864912 0.79 ALDH1A1 (0.55) CYP3A4TDP1ALDH1A1TSHRGFER
SCHEMBL6020612 0.79 CYP3A4 (0.62) CYP3A4TDP1ALDH1A1TSHRGFER
Methyl Alcohol SCHEMBL28089962 0.77 TSHR (0.52) CYP3A4TDP1ALDH1A1TSHRGFER
SCHEMBL398262 0.75 MAOB (0.37) CYP3A4TDP1ALDH1A1TSHRGFER
SCHEMBL7261403 0.73 TOP1 (0.65)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2408572-A1 COMPOSITE STRUCTURED ORGANIC FILMS Xerox Corporation (US) 2012-01-25 EP disclosed
EP-2403656-A1 ELECTRONIC DEVICES COMPRISING STRUCTURED ORGANIC FILMS Xerox Corporation (US) 2012-01-11 EP disclosed
WO-2010102038-A1 ELECTRONIC DEVICES COMPRISING STRUCTURED ORGANIC FILMS XEROX CORPORATION (US) 2010-09-10 WO disclosed
WO-2010102027-A1 COMPOSITE STRUCTURED ORGANIC FILMS XEROX CORPORATION (US) 2010-09-10 WO disclosed