SCHEMBL3796571

SCHEMBL3796571

O=S(=O)(Cc1ccc(SSc2ccc(CS(=O)(=O)c3ccccc3)cc2)cc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.59
HSD17B10 Q99714 2/20 0.51
TSHR P16473 2/20 0.51
PSIP1 O75475 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.41
HPGD P15428 1/20 0.41
MGLL Q99685 1/20 0.41
FAAH O00519 1/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
ELANE P08246 1/20 0.41
PRTN3 P24158 1/20 0.41
PRSS3 P35030 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA5A P35218 1/20 0.41
CA9 Q16790 1/20 0.41
DAO P14920 1/20 0.41
MMP3 P08254 1/20 0.40
MMP8 P22894 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzylsulfonylbenzene SCHEMBL780337 0.83 TSHR (0.68) MAPTHSD17B10TSHRPSIP1SMN1; SMN2
SCHEMBL945222 0.81 HDAC1 (0.48) MAPTPSIP1CA1CA2MMP3
Benzylsulfonylbenzene SCHEMBL1877584 0.81 TSHR (0.66) MAPTHSD17B10TSHRPSIP1SMN1; SMN2
SCHEMBL776229 0.78 MAPT (0.61) MAPTHSD17B10TSHRPSIP1FAAH
SCHEMBL9820015 0.78 MAPT (0.61) MAPTHSD17B10TSHRPSIP1SMN1; SMN2
SCHEMBL14445952 0.78 MAPT (0.61) MAPTHSD17B10TSHRPSIP1SMN1; SMN2
SCHEMBL11114440 0.78 MAPT (0.61) MAPTHSD17B10TSHRPSIP1SMN1; SMN2
SCHEMBL9440227 0.78 MAPT (0.61) MAPTHSD17B10TSHRPSIP1SMN1; SMN2
SCHEMBL22511307 0.78 MAPT (0.61) MAPTHSD17B10TSHRPSIP1SMN1; SMN2
SCHEMBL3668383 0.78 MAPT (0.61) MAPTHSD17B10TSHRPSIP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110306798-A1 Methods for Producing Arylsulfur Pentafluorides UBE INDUSTRIES, LTD. (JP) 2011-12-15 US disclosed
US-7820864-B2 2,3,4,5,6-pentafluorophenylsulfur pentafluoride; as intermediates for introduce sulfur pentafluoride groups into various commercial organic molecules; liquid crystals, fungicides, herbicides, and insecticides IM&T RESEARCH, INC. (US) 2010-10-26 US disclosed
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA MAPT 3764/4885HSD17B10 2421/4885TSHR 76/4885
US-20110306798-A1 Methods for Producing Arylsulfur Pentafluorides PFAS, ARSA, HDHD5 MAPT 4331/4885HSD17B10 1858/4885TSHR 93/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.