Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 3/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL703718 | 0.90 | CYP3A4 (0.43) | LMNADNM1TSHRCYP3A4L3MBTL1 | |
| SCHEMBL3482193 | 0.88 | CYP3A4 (0.48) | LMNATSHRPRSS1PRSS2PRSS3 | |
| SCHEMBL16497542 | 0.86 | CYP3A4 (0.41) | LMNADNM1TSHRCYP3A4L3MBTL1 | |
| SCHEMBL2895314 | 0.81 | CYP3A4 (0.55) | LMNATSHRPRSS1PRSS2PRSS3 | |
| SCHEMBL1776604 | 0.80 | LMNA (0.54) | LMNADNM1TSHRTHRBPRSS1 | |
| SCHEMBL8387794 | 0.80 | LMNA (0.54) | LMNADNM1TSHRTHRBPRSS1 | |
| SCHEMBL2188453 | 0.80 | LMNA (0.54) | LMNADNM1TSHRTHRBPRSS1 | |
| SCHEMBL21641724 | 0.80 | LMNA (0.54) | LMNADNM1TSHRTHRBPRSS1 | |
| SCHEMBL574982 | 0.80 | LMNA (0.54) | LMNADNM1TSHRTHRBPRSS1 | |
| SCHEMBL20253212 | 0.80 | LMNA (0.54) | LMNADNM1TSHRTHRBPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100012880-A1 | MAGNETIC PARTICLES AND METHODS OF MAKING AND USING THE SAME | COLUMBUS NANOWORKS, INC. (US) | 2010-01-21 | — | — | US | disclosed |
| EP-2062271-A2 | MAGNETIC PARTICLES AND METHODS OF MAKING AND USING THE SAME | Columbus Nanoworks, Inc. (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008030862-A2 | MAGNETIC PARTICLES AND METHODS OF MAKING AND USING THE SAME | COLUMBUS NANOWORKS, INC. (US) | 2008-03-13 | — | — | WO | disclosed |