Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 0.82 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.81 |
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702530 | 0.83 | CYP1A2 (0.92) | ALDH1A1MAPK1LMNACYP1A2CYP3A4 | |
| SCHEMBL24029199 | 0.82 | ALDH1A1 (0.70) | ALDH1A1TSHRLMNACYP1A2CYP3A4 | |
| SCHEMBL24210197 | 0.81 | ALDH1A1 (0.83) | ALDH1A1TSHRMAPK1LMNAMAPT | |
| SCHEMBL1611132 | 0.79 | ALDH1A1 (0.67) | ALDH1A1MAPK1LMNACYP1A2CYP3A4 | |
| SCHEMBL27782464 | 0.79 | SMN1; SMN2 (0.76) | ALDH1A1TSHRMAPK1LMNAMAPT | |
| SCHEMBL11515264 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TSHRMAPK1MAPTCYP1A2 | |
| SCHEMBL8188675 | 0.77 | ALDH1A1 (0.72) | ALDH1A1MAPK1MAPTCYP1A2CYP3A4 | |
| SCHEMBL27804013 | 0.74 | ALDH1A1 (0.72) | ALDH1A1TSHRMAPK1MAPTCYP1A2 | |
| SCHEMBL24019615 | 0.74 | NPSR1 (0.62) | ALDH1A1TSHRMAPK1LMNACYP1A2 | |
| SCHEMBL3655081 | 0.73 | PTPN1 (0.67) | ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791299-B2 | Compounds for the inhibition of herpes viruses | UNIVERSITE LAVAL (CA) | 2014-07-29 | — | — | US | claimed |
| US-20120157538-A1 | Compounds for the Inhibition of Herpes Viruses | UNIVERSITE LAVAL (CA) | 2012-06-21 | — | — | US | claimed |
| WO-2010132992-A1 | COMPOUNDS FOR THE INHIBITION OF HERPESVIRUSES | UNIVERSITé LAVAL (CA) | 2010-11-25 | — | — | WO | claimed |
| US-8791299-B2 | Compounds for the inhibition of herpes viruses | UNIVERSITE LAVAL (CA) | 2014-07-29 | — | — | US | disclosed |
| US-20120157538-A1 | Compounds for the Inhibition of Herpes Viruses | UNIVERSITE LAVAL (CA) | 2012-06-21 | — | — | US | disclosed |
| WO-2010132992-A1 | COMPOUNDS FOR THE INHIBITION OF HERPESVIRUSES | UNIVERSITé LAVAL (CA) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157538-A1 | Compounds for the Inhibition of Herpes Viruses | NOS3, NOS1, DNA2 | ALDH1A1 4683/4885TSHR 4271/4885MAPK1 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.