SCHEMBL3796992

SCHEMBL3796992

CCCCCCCCCCC#C[Si](C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 5/20 0.43
HMGCR P04035 3/20 0.43
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
RECQL P46063 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
KCNH2 Q12809 1/20 0.37
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
ALOX12 P18054 1/20 0.36
BLM P54132 1/20 0.36
KMT2A Q03164 1/20 0.36
MCL1 Q07820 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
EPHX2 P34913 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9628541 1.00 PTPN7 (0.43) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL3796995 1.00 PTPN7 (0.43) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL5865499 1.00 PTPN7 (0.43) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL31519146 1.00 PTPN7 (0.43) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL9336077 1.00 PTPN7 (0.43) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL2121918 0.97 PTPN7 (0.40) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL588584 0.90 TSHR (0.39) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL31725737 0.89 RAB9A (0.38) PTPN7HMGCR
SCHEMBL16420274 0.87 RAB9A (0.33)
SCHEMBL29979993 0.84 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100198521-A1 CHEMICALLY SENSITIVE FIELD EFFECT TRANSISTORS AND USES THEREOF IN ELECTRONIC NOSE DEVICES TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) 2010-08-05 US claimed
US-11243186-B2 Chemically sensitive field effect transistors and uses thereof in electronic nose devices TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) 2022-02-08 US disclosed
US-20180282155-A1 CHEMICALLY SENSITIVE FIELD EFFECT TRANSISTORS AND USES THEREOF IN ELECTRONIC NOSE DEVICES TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. 2018-10-04 US disclosed
US-10011481-B2 Chemically sensitive field effect transistors and uses thereof in electronic nose devices TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) 2018-07-03 US disclosed
US-20100198521-A1 CHEMICALLY SENSITIVE FIELD EFFECT TRANSISTORS AND USES THEREOF IN ELECTRONIC NOSE DEVICES TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) 2010-08-05 US disclosed