SCHEMBL379706

SCHEMBL379706

CCO[Si](CCC[N+](=O)[O-])(OCC)OCC

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28321914 0.98 ALDH1A1 (0.46) ALDH1A1TSHRTDP1
SCHEMBL28306094 0.98 ALDH1A1 (0.46) ALDH1A1TSHRTDP1
SCHEMBL11670999 0.87 ALDH1A1 (0.41) ALDH1A1TSHRTDP1
SCHEMBL380203 0.78 ALDH1A1 (0.46) ALDH1A1TSHRTDP1
SCHEMBL28310679 0.77 ALDH1A1 (0.44) ALDH1A1TSHRTDP1
Nitric Acid SCHEMBL16588775 0.75 CYP1A2 (0.33)
SCHEMBL329186 0.74
SCHEMBL315210 0.74
SCHEMBL32671271 0.73 TSHR (0.41) ALDH1A1TSHR
SCHEMBL477797 0.71 LMNA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1999 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250188250-A1 FUNCTIONALIZED SILICA, MASTERBATCH COMPRISING THE SAME, AND RUBBER ARTICLES COMPRISING THE SAME THE GOODYEAR TIRE & RUBBER COMPANY 2025-06-12 US claimed
CN-120118396-A Functionalized silica, masterbatch comprising same, and rubber article comprising same 固特异轮胎和橡胶公司 2025-06-10 CN claimed
CN-115602045-A Metal worker card and manufacturing method and cleaning method thereof 深圳市中孚能电气设备有限公司(CN) 2023-01-13 CN claimed
US-20130317244-A1 ORGANIC-INORGANIC HYBRID CHIRAL SORBENT AND PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-11-28 US claimed
US-20100286425-A1 ORGANIC-INORGANIC HYBRID CHIRAL SORBENT AND PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2010-11-11 US claimed
EP-2066440-A1 ORGANIC-INORGANIC HYBRID CHIRAL SORBENT AND PROCESS FOR THE PREPARATION THEREOF Council of Scientific & Industrial Research (IN) 2009-06-10 EP claimed
WO-2008038300-A1 ORGANIC-INORGANIC HYBRID CHIRAL SORBENT AND PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2008-04-03 WO claimed
US-20040014869-A1 Method for preparing silica filled elastomeric compositions WONG WAI KEUNG (BE) 2004-01-22 US claimed
EP-1309657-A2 METHOD FOR PREPARING SILICA FILLED ELASTOMERIC COMPOSITIONS Exxonmobil Chemical Patents Inc. (US) 2003-05-14 EP claimed
WO-2001096463-A2 METHOD FOR PREPARING SILICA FILLED ELASTOMERIC COMPOSITIONS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2001-12-20 WO claimed
EP-0663421-B1 Tyre tread prepared with a rubber composition UNIROYAL ENGLEBERT GMBH (DE) 1999-04-28 EP claimed
EP-0708137-B1 Vulcanizable rubber composition and tire prepared therefrom UNIROYAL ENGLEBERT GMBH (DE) 1999-03-31 EP claimed
EP-0708136-B1 Rubber blend and tread base prepared therefrom UNIROYAL ENGLEBERT GMBH (DE) 1999-03-03 EP claimed
EP-0708137-A1 Vulcanizable rubber composition and tire prepared therefrom Uniroyal Englebert Reifen GmbH (DE) 1996-04-24 EP claimed
EP-0708136-A1 Rubber blend and tread base prepared therefrom Uniroyal Englebert Reifen GmbH (DE) 1996-04-24 EP claimed
EP-0663421-A1 Rubber composition and tire tread prepared therewith Uniroyal Englebert Reifen GmbH (DE) 1995-07-19 EP claimed
EP-4748589-A1 HEAVY-DUTY TIRE Sumitomo Rubber Industries, Ltd. (JP) 2026-05-27 EP disclosed
US-20260138400-A1 TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-05-21 US disclosed
EP-0541367-A1 Flame-retardant rubber compositions BRIDGESTONE CORPORATION (JP) 1993-05-12 EP disclosed
EP-0447066-A1 Pneumatic tyres Bridgestone Corporation (JP) 1991-09-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138400-A1 TIRE GYS1, RAE1, POT1 ALDH1A1 1695/4885TSHR 973/4885TDP1 304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.