Alipamide

Alipamide

SCHEMBL3797100

C1CCCCC1.CN(C)NC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.64
OPRD1 P41143 1/20 0.64
KDM4E B2RXH2 1/20 0.58
LMNA P02545 1/20 0.58
GLA P06280 1/20 0.58
MAPT P10636 1/20 0.58
HTT P42858 1/20 0.58
HSD17B10 Q99714 1/20 0.58
CA1 P00915 14/20 0.57
CA2 P00918 14/20 0.57
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
STAT3 P40763 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alipamide SCHEMBL3793041 1.00 OPRM1 (0.64) OPRM1OPRD1KDM4ELMNAGLA
Alipamide SCHEMBL120853 0.96 CA1 (0.61) OPRM1OPRD1KDM4ELMNAGLA
Alipamide SCHEMBL28278565 0.94 CA1 (0.60) OPRM1OPRD1KDM4ELMNAGLA
SCHEMBL13687260 0.80 CA1 (0.66) KDM4ELMNAGLAMAPTHTT
SCHEMBL1272484 0.78 CA1 (0.71) CA1CA2
SCHEMBL11348046 0.78 KDM4E (0.54) OPRM1OPRD1KDM4ELMNAGLA
SCHEMBL31670530 0.77 CNR2 (0.73) KDM4ELMNAGLAMAPTHTT
SCHEMBL11560883 0.77 CA1 (0.55) OPRM1OPRD1KDM4ELMNAGLA
SCHEMBL13687209 0.76 CA1 (0.72) OPRM1OPRD1CA1CA2
SCHEMBL10829518 0.76 CA1 (0.60) OPRM1OPRD1CA1CA2STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763357-B2 Polymer composite synthesis in supercritical fluids CHARPENTIER PAUL A 2010-07-27 US disclosed
US-20060194928-A1 Polymer composite synthesis in supercritical fluids CHARPENTIER PAUL A 2006-08-31 US disclosed