Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL3797182

Cc1cccc(OS(=O)(=O)O)c1C.S

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.46
GAA P10253 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
POLB P06746 1/20 0.42
HTR6 P50406 1/20 0.40
FABP1 P07148 1/20 0.40
HTR1B P28222 1/20 0.40
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
TRPA1 O75762 1/20 0.39
ATM Q13315 1/20 0.39
LMNA P02545 1/20 0.39
RAB9A P51151 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SLC22A6 Q4U2R8 1/20 0.39
CASP1 P29466 1/20 0.38
ALDH1A1 P00352 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4120032 0.98 MAPT (0.47) MAPTGAAMEN1KMT2AESR1
SCHEMBL777549 0.82 SLC22A6 (0.46) GAAMEN1KMT2AESR1ESR2
SCHEMBL6550906 0.82 MAPT (0.50) MAPTGAAMEN1KMT2AESR1
SCHEMBL17157291 0.81 ALDH1A1 (0.48) MAPTGAAMEN1KMT2AESR1
SCHEMBL6938262 0.80 MAPT (0.48) MAPTGAAMEN1KMT2AESR1
SCHEMBL29497718 0.80 MAPT (0.48) MAPTGAAMEN1KMT2AESR1
Ammonia Solution, Strong SCHEMBL28878776 0.80 SLC22A6 (0.44) GAAMEN1KMT2AESR1ESR2
SCHEMBL17456550 0.80 SLC22A6 (0.44) GAAMEN1KMT2AESR1ESR2
SCHEMBL9299728 0.79 CD44 (0.42) MAPTGAAMEN1KMT2AESR1
SCHEMBL4121193 0.79 MEN1 (0.39) MAPTGAAMEN1KMT2AESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8283104-B2 Sulfonate and its derivative, photosensitive acid generator, and resist composition and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-10-09 US disclosed
US-20100209827-A1 NOVEL SULFONATE AND ITS DERIVATIVE, PHOTOSENSITIVE ACID GENERATOR, AND RESIST COMPOSITION AND PATTERNING PROCESS USING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100209827-A1 NOVEL SULFONATE AND ITS DERIVATIVE, PHOTOSENSITIVE ACID GENERATOR, AND RESIST COMPOSITION AND PATTERNING PROCESS USING THE SAME DAP3, MRPS23, ASIC3 MAPT 3189/4885GAA 3755/4885MEN1 4475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.