Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29497718 | 1.00 | MAPT (0.48) | MAPTKEAP1NFE2L2KMT2AKDM4E | |
| SCHEMBL3843587 | 0.89 | KMT2A (0.49) | MAPTKEAP1NFE2L2KMT2AKDM4E | |
| SCHEMBL6550906 | 0.85 | MAPT (0.50) | MAPTKEAP1NFE2L2KMT2AKDM4E | |
| SCHEMBL6937363 | 0.83 | ALDH1A1 (0.45) | KMT2AKDM4EALDH1A1GAAMEN1 | |
| SCHEMBL30821607 | 0.83 | ALDH1A1 (0.45) | KMT2AKDM4EALDH1A1GAAMEN1 | |
| SCHEMBL11973731 | 0.82 | MAPT (0.52) | MAPTKEAP1NFE2L2KMT2AGAA | |
| SCHEMBL4120032 | 0.82 | MAPT (0.47) | MAPTKEAP1NFE2L2KMT2AKDM4E | |
| SCHEMBL9957659 | 0.82 | KMT2A (0.44) | MAPTNFE2L2KMT2AKDM4EALDH1A1 | |
| SCHEMBL14500654 | 0.82 | TSHR (0.46) | MAPTKEAP1NFE2L2KMT2AKDM4E | |
| Hydrogen Sulfide SCHEMBL3797182 | 0.80 | MAPT (0.46) | MAPTKEAP1NFE2L2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114702411-A | Method for producing 1, 2-benzenedimethanol compound | 高文作物保护公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-108602765-B | Method for producing 1, 2-benzenedimethanol compound | 高文有限公司 | 2022-05-03 | — | — | CN | disclosed |
| US-11274076-B2 | Process for preparing 1, 2-benzenedimethanol compound | GOWAN COMPANY, L.L.C. (US) | 2022-03-15 | — | — | US | disclosed |
| EP-3415496-B1 | PROCESS FOR PREPARING 1,2-BENZENEDIMETHANOL COMPOUND | GOWAN COMPANY L L C (US) | 2021-07-21 | — | — | EP | disclosed |
| US-20200399263-A1 | PROCESS FOR PREPARING 1, 2-BENZENEDIMETHANOL COMPOUND | BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT | 2020-12-24 | — | — | US | disclosed |
| EP-3429355-B1 | SUBSTITUTED SULFONYLAMIDE FOR COMBATING ANIMAL PESTS | BAYER CROPSCIENCE AG (DE) | 2020-02-05 | — | — | EP | disclosed |
| EP-2949655-B1 | REACTION CATALYST FOR CROSS COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND | HOKKO CHEM IND CO (JP) | 2019-05-15 | — | — | EP | disclosed |
| EP-3415496-A1 | METHOD FOR PRODUCING 1, 2-BENZENE DIMETHANOL COMPOUND | SDS Biotech K. K. (JP) | 2018-12-19 | — | — | EP | disclosed |
| US-9707551-B2 | Reaction catalyst for cross-coupling and method for manufacturing aromatic compound | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-07-18 | — | — | US | disclosed |
| US-20150360214-A1 | REACTION CATALYST FOR CROSS-COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-12-17 | — | — | US | disclosed |
| EP-2949655-A1 | REACTION CATALYST FOR CROSS COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND | Hokko Chemical Industry Co., Ltd. (JP) | 2015-12-02 | — | — | EP | disclosed |
| CN-105008378-A | Reaction catalyst for cross coupling and method for manufacturing aromatic compound | HOKKO CHEM IND CO | 2015-10-28 | — | — | CN | disclosed |
| WO-2013054351-A1 | HETEROCYCLIC COMPOUNDS | CADILA HEALTHCARE LIMITED (IN) | 2013-04-18 | — | — | WO | disclosed |
| EP-1167372-B1 | 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst | TAKASAGO PERFUMERY CO LTD (JP) | 2003-12-10 | — | — | EP | disclosed |
| US-6455720-B1 | AS CATALYSTS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-09-24 | — | — | US | disclosed |
| US-20020058837-A1 | 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-05-16 | — | — | US | disclosed |
| US-6365776-B1 | FROM ORGANOHALOGEN COMPOUND AND AMINE USING PALLADIUM COMPOUND CATALYST AND PROMOTER | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-04-02 | — | — | US | disclosed |
| US-20020035295-A1 | PROCESS FOR PRODUCING AROMATIC AMINES | TAKASAGO INTERNATIONAL CORPORATION | 2002-03-21 | — | — | US | disclosed |
| EP-1167372-A1 | 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst | Takasago International Corporation (JP) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035295-A1 | PROCESS FOR PRODUCING AROMATIC AMINES | TYR, DDC, PNMT | MAPT 1945/4885KEAP1 559/4885NFE2L2 446/4885 |
| US-20020058837-A1 | 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst | DDT, PDCD11, PLD2 | MAPT 4856/4885KEAP1 468/4885NFE2L2 420/4885 |
| US-20200399263-A1 | PROCESS FOR PREPARING 1, 2-BENZENEDIMETHANOL COMPOUND | ADH1A, ADH1C, CYP2E1 | MAPT 3757/4885KEAP1 1668/4885NFE2L2 728/4885 |
| US-20150360214-A1 | REACTION CATALYST FOR CROSS-COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND | ALK, HRH4, HRH3 | MAPT 4800/4885KEAP1 4208/4885NFE2L2 4108/4885 |
| US-11274076-B2 | Process for preparing 1, 2-benzenedimethanol compound | ADH1A, ADH1C, CYP2E1 | MAPT 3757/4885KEAP1 1668/4885NFE2L2 728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.