SCHEMBL379726

SCHEMBL379726

CCOC([SiH3])(CN(CC)CC)OCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL379738 0.77
SCHEMBL379569 0.77
SCHEMBL379573 0.76 SIGMAR1 (0.31)
SCHEMBL379492 0.73 SIGMAR1 (0.36)
SCHEMBL380329 0.72 SIGMAR1 (0.42)
SCHEMBL3915001 0.70
SCHEMBL7549927 0.69
SCHEMBL705648 0.67
SCHEMBL2270325 0.67 PAX8 (0.31)
SCHEMBL1491903 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4541800-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME Shin-Etsu Chemical Co., Ltd. (JP) 2025-04-23 EP disclosed
US-20250122230-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-04-17 US disclosed
EP-2511334-B1 TYRE RUBBER COMPOSITION AND PNEUMATIC TYRE SUMITOMO RUBBER IND (JP) 2018-04-25 EP disclosed
EP-2174801-B1 Rubber composition and pneumatic tire SUMITOMO RUBBER IND (JP) 2016-10-19 EP disclosed
US-8800621-B2 Rubber composition and tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-08-12 US disclosed
US-20120283354-A1 TYRE RUBBER COMPOSITION AND PNEUMATIC TYRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-11-08 US disclosed
EP-2366558-B1 Tire rubber composition and heavy-load tire SUMITOMO RUBBER IND (JP) 2012-10-31 EP disclosed
EP-2511334-A1 TYRE RUBBER COMPOSITION AND PNEUMATIC TYRE Sumitomo Rubber Industries, Ltd. (JP) 2012-10-17 EP disclosed
EP-2366557-B1 Tire rubber composition and pneumatic tire SUMITOMO RUBBER IND (JP) 2012-05-23 EP disclosed
US-8163821-B2 Tire rubber composition and heavy-load tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-04-24 US disclosed
EP-2196324-A1 Tread rubber composition for studless tire and studless tire Sumitomo Rubber Industries, Ltd. (JP) 2010-06-16 EP disclosed
US-20100144954-A1 TREAD RUBBER COMPOSITION FOR STUDLESS TIRE AND STUDLESS TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-06-10 US disclosed
EP-2184317-A1 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-12 EP disclosed
US-20100108213-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-05-06 US disclosed
EP-2174801-A2 Rubber composition and pneumatic tire Sumitomo Rubber Industries, Ltd. (JP) 2010-04-14 EP disclosed
US-20100084065-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-08 US disclosed
US-7276615-B2 Organofunctional surface-modified metal oxides WACKER CHEMIE AG (DE) 2007-10-02 US disclosed
EP-1473296-B1 Organofunctional surface modified metal oxides WACKER CHEMIE AG (DE) 2006-08-02 EP disclosed
US-20040220419-A1 Organofunctional surface-modified metal oxides WACKER-CHEMIE GMBH (DE) 2004-11-04 US disclosed
EP-1473296-A1 Organofunctional surface modified metal oxides Wacker-Chemie GmbH (DE) 2004-11-03 EP disclosed