Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27695762 | 0.80 | HPGD (0.44) | LRRK2CHEK1MAP4K4ABL1NTRK1 | |
| SCHEMBL3703224 | 0.76 | TSHR (0.41) | ARTSHRHPGDSMN1; SMN2LMNA | |
| SCHEMBL28343710 | 0.75 | MAOB (0.41) | LRRK2CHEK1MAP4K4ABL1NTRK1 | |
| SCHEMBL20147802 | 0.75 | ADORA1 (0.52) | ADORA2AADORA1LRRK2ARCHEK1 | |
| Methane SCHEMBL28398053 | 0.74 | TSHR (0.39) | ARTSHRHPGDSMN1; SMN2LMNA | |
| Methane SCHEMBL27546364 | 0.74 | TSHR (0.39) | ARTSHRHPGDSMN1; SMN2LMNA | |
| SCHEMBL5025375 | 0.73 | HTR7 (0.55) | ADORA1LRRK2CHEK1MAP4K4ABL1 | |
| SCHEMBL7774109 | 0.71 | PTGER1 (0.38) | ADORA2AADORA1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11422210 | 0.71 | ACHE (0.46) | ADORA1LRRK2CHEK1MAP4K4ABL1 | |
| SCHEMBL28414965 | 0.70 | ACHE (0.55) | ADORA2AADORA1LRRK2CHEK1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010054975-A1 | PROCESS FOR THE DISTRIBUTION OF SILICATES IN COATING MATERIALS | BASF SE (DE) | 2010-05-20 | — | — | WO | disclosed |