SCHEMBL20147802

SCHEMBL20147802

Cc1cccc(-c2cccc(C)c2C#N)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 3/20 0.52
ADORA2A P29274 2/20 0.52
ADORA2B P29275 1/20 0.46
AR P10275 2/20 0.43
LRRK2 Q5S007 3/20 0.43
CYP1A2 P05177 1/20 0.42
CYP2C19 P33261 1/20 0.42
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 2/20 0.39
HPGD P15428 2/20 0.39
KMT2A Q03164 2/20 0.39
POLB P06746 1/20 0.39
KDM4E B2RXH2 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
RXFP1 Q9HBX9 1/20 0.39
CTSS P25774 1/20 0.39
CTSK P43235 1/20 0.39
HTR7 P34969 1/20 0.39
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18406701 0.84 ADORA2A (0.51) ADORA1ADORA2AADORA2BARLRRK2
SCHEMBL21189094 0.84 ADRA2C (0.49) ADORA1ADORA2AADORA2BARCYP1A2
SCHEMBL3376658 0.83 ALDH1A1 (0.49) ADORA1ADORA2ACYP1A2CYP2C19ALDH1A1
SCHEMBL23910083 0.78 CD274 (0.48) ADORA1ADORA2AALDH1A1HPGDKDM4E
SCHEMBL5025375 0.77 HTR7 (0.55) ADORA1LRRK2ALDH1A1HPGDKMT2A
SCHEMBL5003746 0.76 GABRG2 (0.56) ADORA1ADORA2AARLRRK2CYP1A2
SCHEMBL23625616 0.76 AR (0.44) ARCYP1A2CYP2C19ALDH1A1MEN1
SCHEMBL8845798 0.75 SMN1; SMN2 (0.45) ADORA1ADORA2ACYP1A2CYP2C19ALDH1A1
SCHEMBL11422210 0.75 ACHE (0.46) ADORA1LRRK2ALDH1A1HPGDPOLB
SCHEMBL3797264 0.75 ADORA2A (0.40) ADORA1ADORA2AADORA2BARLRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180134844-A1 Block Copolymer, Ion-Exchange Membrane And Method Of Preparing Block Copolymer KOREA INSTITUTE OF ENERGY RESEARCH (KR) 2018-05-17 US disclosed