Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | HTR6 | P50406 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | VEGFA | P15692 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | UBE2N | P61088 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20488209 | 0.84 | L3MBTL1 (0.55) | L3MBTL1HTR6CA1CA2RAPGEF4 | |
| SCHEMBL28335381 | 0.81 | L3MBTL1 (0.51) | L3MBTL1HTR6CA1CA2RAPGEF4 | |
| SCHEMBL1934468 | 0.79 | ALDH1A1 (0.39) | L3MBTL1NOD1VEGFAEGLN1KDM4E | |
| SCHEMBL3797631 | 0.79 | KDM4E (0.51) | L3MBTL1CA1CA2NOD1KDM4E | |
| SCHEMBL28554876 | 0.78 | L3MBTL1 (0.48) | L3MBTL1HTR6CA1CA2RAPGEF4 | |
| SCHEMBL30213799 | 0.78 | L3MBTL1 (0.48) | L3MBTL1HTR6CA1CA2RAPGEF4 | |
| SCHEMBL10008513 | 0.77 | L3MBTL1 (0.50) | L3MBTL1HTR6CA1CA2RAPGEF4 | |
| SCHEMBL18855947 | 0.76 | HTR6 (0.49) | L3MBTL1HTR6RAPGEF4BRD4POLB | |
| SCHEMBL1933398 | 0.76 | L3MBTL1 (0.44) | L3MBTL1HTR6CA1CA2RAPGEF4 | |
| SCHEMBL20488438 | 0.76 | HTR6 (0.48) | L3MBTL1HTR6RAPGEF4CYP19A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010117425-A1 | CERTAIN SUBSTITUTED PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | BIOGEN IDEC MA INC. (US) | 2010-10-14 | — | — | WO | disclosed |