Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20097983 | 0.75 | KIF11 (0.39) | AAK1KIF11USP2RAB9ACYP3A4 | |
| SCHEMBL8744330 | 0.70 | TAAR1 (0.60) | KIF11USP2RAB9A | |
| SCHEMBL12197886 | 0.69 | AAK1 (0.40) | AAK1KIF11USP2RAB9ACYP3A4 | |
| SCHEMBL8057442 | 0.68 | RAB9A (0.44) | KIF11USP2RAB9A | |
| SCHEMBL2705790 | 0.67 | KIF11 (0.48) | KIF11USP2RAB9A | |
| SCHEMBL30947614 | 0.67 | KIF11 (0.48) | KIF11USP2RAB9A | |
| SCHEMBL18682641 | 0.66 | SHBG (0.56) | KIF11USP2RAB9ACYP3A4 | |
| SCHEMBL22317811 | 0.66 | HDAC8 (0.42) | KIF11USP2RAB9A | |
| SCHEMBL10487429 | 0.66 | KIF11 (0.41) | KIF11USP2RAB9A | |
| SCHEMBL16455578 | 0.66 | KIF11 (0.41) | KIF11USP2RAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190431-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST FOR TREATING OR CONTROLLING ANTERIOR-SEGMENT INFLAMMATION | Bausch & Lomb Incorporated (US) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009023471-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST FOR TREATING OR CONTROLLING ANTERIOR-SEGMENT INFLAMMATION | BAUSCH & LOMB INCORPORATED (US) | 2009-02-19 | — | — | WO | disclosed |