SCHEMBL3798618

SCHEMBL3798618

O=C(Cl)CCC[Si](Cl)(Cl)Cl

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
TP53 P04637 1/20 0.48
TSHR P16473 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11491111 0.82
SCHEMBL10894480 0.79 ALDH1A1 (0.50) ALDH1A1TP53TSHR
SCHEMBL9066514 0.79 ALDH1A1 (0.50) ALDH1A1TP53TSHR
SCHEMBL19770572 0.78 LMNA (0.53) ALDH1A1TSHR
SCHEMBL11151060 0.76 ALDH1A1 (0.52) ALDH1A1TP53TSHR
Hydrochloric Acid SCHEMBL3798619 0.76 LMNA (0.50) ALDH1A1TSHR
SCHEMBL11205937 0.76 ALDH1A1 (0.52) ALDH1A1TP53TSHR
SCHEMBL3798799 0.75 ALDH1A1 (0.52) ALDH1A1TP53TSHR
SCHEMBL180666 0.75
SCHEMBL132364 0.75 TSHR (0.67) ALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8329263-B2 Method of coating a particle AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-12-11 US disclosed
US-20100276310-A1 METHOD OF COATING A PARTICLE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-11-04 US disclosed
WO-2009029053-A1 METHOD OF COATING A PARTICLE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-03-05 WO disclosed