Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | FABP7 | O15540 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29527476 | 1.00 | MCHR1 (0.53) | MCHR1KDM4EMAPTGAACARM1 | |
| SCHEMBL1134126 | 0.98 | MCHR1 (0.50) | MCHR1KDM4EMAPTGAACARM1 | |
| SCHEMBL6905082 | 0.90 | ALDH1A1 (0.48) | MCHR1KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL2242864 | 0.85 | MCHR1 (0.51) | MCHR1CARM1PRMT1ADRA2BCSNK2A1 | |
| SCHEMBL5344402 | 0.83 | MCHR1 (0.49) | MCHR1CARM1PRMT1ADRA2BCSNK2A1 | |
| Aniline SCHEMBL22169159 | 0.82 | ALDH1A1 (0.42) | MCHR1KDM4EMAPTALDH1A1ADRA2B | |
| SCHEMBL22684133 | 0.82 | MCHR1 (0.51) | MCHR1KDM4EMAPTGAACARM1 | |
| SCHEMBL13537844 | 0.82 | MCHR1 (0.51) | MCHR1KDM4EMAPTGAACARM1 | |
| SCHEMBL3798831 | 0.81 | KAT2B (0.53) | MCHR1KDM4EMAPTALDH1A1ADRA2B | |
| SCHEMBL9505634 | 0.81 | HRH1 (0.41) | MCHR1KDM4EMAPTGAACARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108409684-B | N- (2-cyclohexyloxyphenyl) amide compound and preparation method and application thereof | 上海晓明检测技术服务有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-108409684-B | N- (2-cyclohexyloxyphenyl) amide compound and preparation method and application thereof | 上海晓明检测技术服务有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-108409684-B | N- (2-cyclohexyloxyphenyl) amide compound and preparation method and application thereof | 上海晓明检测技术服务有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-108409684-B | N- (2-cyclohexyloxyphenyl) amide compound and preparation method and application thereof | 上海晓明检测技术服务有限公司 | 2022-04-12 | — | — | CN | disclosed |
| US-20100143341-A1 | THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | DEVELOGEN AKTIENGESELLSCHAFT (DE) | 2010-06-10 | — | — | US | disclosed |
| EP-1899353-A1 | THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | DeveloGen Aktiengesellschaft (DE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007059905-A9 | THIENOPYRIMIDINES TREATING INFLAMMATORY DISEASES | DEVELOGEN AG (DE) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007059905-A2 | THIENOPYRIMIDINES TREATING INFLAMMATORY DISEASES | DEVELOGEN AKTIENGESELLSCHAFT (DE) | 2007-05-31 | — | — | WO | disclosed |
| WO-2006136402-A1 | THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | DEVELOGEN AKTIENGESELLSCHAFT (DE) | 2006-12-28 | — | — | WO | disclosed |
| EP-0848703-B1 | DERIVATIVES OF BENZOSULPHONAMIDES AS INHIBITORS OF THE ENZYME CYCLO-OXYGENASE II | NYCOMED AUSTRIA GMBH (AT) | 2000-09-27 | — | — | EP | disclosed |
| US-6004948-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | NYCOMED AUSTRIA GMBH (AT) | 1999-12-21 | — | — | US | disclosed |
| EP-0848703-A1 | DERIVATIVES OF BENZOSULPHONAMIDES AS INHIBITORS OF THE ENZYME CYCLO-OXYGENASE II | Nycomed Austria GmbH (AT) | 1998-06-24 | — | — | EP | disclosed |
| EP-0623113-B1 | PYRAZOLE CARBOXANILIDE FUNGICIDES | MONSANTO CO (US) | 1997-03-05 | — | — | EP | disclosed |
| WO-1997003953-A1 | DERIVATIVES OF BENZOSULPHONAMIDES AS INHIBITORS OF THE ENZYME CYCLO-OXYGENASE II | NYCOMED AUSTRIA GMBH (AT) | 1997-02-06 | — | — | WO | disclosed |
| US-5223526-A | For plants | MONSANTO COMPANY (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993011117-A1 | PYRAZOLE CARBOXANILIDE FUNGICIDES | MONSANTO COMPANY (US) | 1993-06-10 | — | — | WO | disclosed |
| EP-0317332-B1 | SULFONANILIDE COMPOUNDS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-4885367-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS; SIDE EFFECT REDUCTION | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1989-12-05 | — | — | US | disclosed |
| EP-0317332-A2 | Sulfonanilide compounds | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1989-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100143341-A1 | THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | DTYMK, CMPK1, PDXK | MCHR1 4661/4885KDM4E 2624/4885MAPT 2500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.