Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.36 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.36 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6905082 | 0.86 | ALDH1A1 (0.48) | HRH1ALDH1A1ADRA2BPTGS1TDP1 | |
| SCHEMBL1134126 | 0.82 | MCHR1 (0.50) | HRH1ALDH1A1ADRA2BPTGS1TDP1 | |
| SCHEMBL3799059 | 0.81 | MCHR1 (0.53) | HRH1ALDH1A1ADRA2BPTGS1TDP1 | |
| SCHEMBL29527476 | 0.81 | MCHR1 (0.53) | HRH1ALDH1A1ADRA2BPTGS1TDP1 | |
| Aniline SCHEMBL22169159 | 0.79 | ALDH1A1 (0.42) | HRH1ALDH1A1ADRA2BPTGS1TDP1 | |
| SCHEMBL8785098 | 0.78 | MCHR1 (0.55) | HRH1ALDH1A1ADRA2BPTGS1TDP1 | |
| SCHEMBL5341225 | 0.78 | HRH1 (0.41) | HRH1ALDH1A1TDP1CACNB4CACNA1A | |
| SCHEMBL2334040 | 0.78 | HRH1 (0.62) | HRH1SLC6A2SLC6A3HTR1ASLC6A4 | |
| SCHEMBL358791 | 0.78 | ALDH1A1 (0.41) | HRH1ALDH1A1ADRA2BPTGS1TDP1 | |
| SCHEMBL3798831 | 0.78 | KAT2B (0.53) | HRH1ALDH1A1ADRA2BPTGS1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317332-B1 | SULFONANILIDE COMPOUNDS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-4885367-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS; SIDE EFFECT REDUCTION | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1989-12-05 | — | — | US | disclosed |
| EP-0317332-A2 | Sulfonanilide compounds | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1989-05-24 | — | — | EP | disclosed |