Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 3/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | MAPKAPK5 | Q8IW41 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3794612 | 0.88 | RAB9A (0.40) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL13918220 | 0.86 | HSD17B10 (0.41) | HSD17B10MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1478160 | 0.78 | HSD17B10 (0.54) | HSD17B10MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1674310 | 0.67 | MAPKAPK5 (0.51) | HSD17B10MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1674143 | 0.62 | DEGS1 (0.71) | HSD17B10MEN1KMT2ANPC1RAB9A | |
| SCHEMBL29385905 | 0.60 | DEGS1 (0.71) | HSD17B10MEN1KMT2ANPC1RAB9A | |
| SCHEMBL21286264 | 0.60 | WNT3A (0.78) | HSD17B10MEN1KMT2ANPC1RAB9A | |
| SCHEMBL20284048 | 0.59 | DEGS1 (1.00) | HSD17B10MEN1KMT2ANPC1RAB9A | |
| SCHEMBL933299 | 0.58 | RAB9A (0.74) | HSD17B10MEN1KMT2ANPC1RAB9A | |
| SCHEMBL22607250 | 0.58 | KMT2A (0.84) | HSD17B10MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029602-B1 | TRIAZOLOPYRAZINE COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE & INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2010-04-21 | — | — | EP | claimed |