Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CISD2 | Q8N5K1 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5409015 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPTKDM4EHSD17B1 | |
| SCHEMBL2624005 | 0.81 | MAPT (0.50) | ALDH1A1TSHRMAPTKDM4ERXFP1 | |
| SCHEMBL767484 | 0.78 | MAPT (0.58) | ALDH1A1TSHRMAPTKDM4ERXFP1 | |
| SCHEMBL1585430 | 0.78 | CA12 (0.44) | ALDH1A1MAPTRXFP1MEN1KMT2A | |
| SCHEMBL30735895 | 0.78 | CA12 (0.44) | ALDH1A1MAPTRXFP1MEN1KMT2A | |
| SCHEMBL16135176 | 0.76 | CA12 (0.57) | MAPTKDM4EHSD17B2MEN1KMT2A | |
| SCHEMBL768559 | 0.75 | MAPT (0.51) | ALDH1A1TSHRMAPTKDM4ERXFP1 | |
| SCHEMBL24717681 | 0.75 | RAB9A (0.43) | ALDH1A1MAPTKDM4ERXFP1MEN1 | |
| SCHEMBL3802232 | 0.75 | KDM4E (0.47) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL31104628 | 0.75 | TAS1R3 (0.47) | ALDH1A1TSHRMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010117425-A1 | CERTAIN SUBSTITUTED PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | BIOGEN IDEC MA INC. (US) | 2010-10-14 | — | — | WO | disclosed |