Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | NQO1 | P15559 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14264112 | 0.85 | NQO1 (0.53) | CA12CA1CA9NQO1CYP19A1 | |
| SCHEMBL294208 | 0.81 | NQO1 (0.56) | CA12CA1CA9NQO1CYP19A1 | |
| SCHEMBL3988879 | 0.81 | NQO1 (0.53) | CA12CA1CA9NQO1CYP19A1 | |
| SCHEMBL8816690 | 0.80 | ALDH1A1 (0.54) | CA12CA1CA9SRD5A1HPGD | |
| SCHEMBL739294 | 0.80 | HSD17B3 (0.68) | CA12CA9CYP19A1HPGDHSD17B10 | |
| SCHEMBL5459900 | 0.79 | CA12 (0.61) | CA12CA1CA9NQO1CYP19A1 | |
| SCHEMBL8372531 | 0.79 | HSD17B3 (0.62) | CA12CA1CA9NQO1CYP19A1 | |
| SCHEMBL18138409 | 0.79 | NQO1 (0.58) | CA12CA1CA9NQO1CYP19A1 | |
| SCHEMBL30486066 | 0.79 | CA12 (0.61) | CA12CA1CA9NQO1CYP19A1 | |
| SCHEMBL4484990 | 0.79 | AURKA (0.48) | HPGDHSD17B10MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556138-B2 | Method of treatment for acne and an anti-acne formulation | Piramal Enterprises Limited (IN) | 2017-01-31 | — | — | US | disclosed |
| US-20150335691-A1 | PLANT EXTRACT OBTAINED FROM KIELMEYERA AUREOVINOSA WHICH HAS ANTIBIOTIC ACTIVITY, ISOLATED CHEMICAL COMPOUND, COMPOSITIONS COMPRISING SAME, USES THEREOF AND METHODS FOR PREVENTING AND TREATING BACTERIAL INFECTIONS | EXTRACTA MOLÉCULAS NATURAIS S/A (BR) | 2015-11-26 | — | — | US | disclosed |
| EP-2825164-A2 | A METHOD OF TREATMENT FOR ACNE AND AN ANTI-ACNE FORMULATION | Piramal Enterprises Limited (IN) | 2015-01-21 | — | — | EP | disclosed |
| US-20150011619-A1 | METHOD OF TREATMENT FOR ACNE AND AN ANTI-ACNE FORMULATION | Piramal Enterprises Limited (IN) | 2015-01-08 | — | — | US | disclosed |
| CN-104203229-A | A method of treatment for acne and an anti-acne formulation | PIRAMAL ENTPR LTD | 2014-12-10 | — | — | CN | disclosed |
| EP-2735311-A1 | PLANT EXTRACT OBTAINED FROM KIELMEYERA AUREOVINOSA WHICH HAS ANTIBIOTIC ACTIVITY, ISOLATED CHEMICAL COMPOUND, COMPOSITIONS COMPRISING SAME, USES THEREOF AND METHODS FOR PREVENTING AND TREATING BACTERIAL INFECTIONS | Extracta Moléculas Naturais S/A (BR) | 2014-05-28 | — | — | EP | disclosed |
| WO-2013164841-A2 | A METHOD OF TREATMENT FOR ACNE AND AN ANTI-ACNE FORMULATION | Piramal Enterprises Limited (IN) | 2013-11-07 | — | — | WO | disclosed |
| US-7846965-B2 | a non-steroidal sulphamate compound such as 6-Oxo-8,9,10,11-tetrahydro-7H-cyclohepta-[c][1]benzopyran-3-O-sulphamate, suitable for use as an inhibitor of estrone sulphatase, for the treatment of endocrine-dependent cancers and tumors, such as the breast and endometrium | STERIX LIMITED (GB) | 2010-12-07 | — | — | US | disclosed |
| US-20070173531-A1 | Compound | REED MICHAEL J | 2007-07-26 | — | — | US | disclosed |
| US-7202272-B2 | Compound | STERIX, LTD. (GB) | 2007-04-10 | — | — | US | disclosed |
| US-6921776-B1 | Compound | STERIX LIMITED (GB) | 2005-07-26 | — | — | US | disclosed |
| US-20050154050-A1 | Compound | REED MICHAEL J (GB) | 2005-07-14 | — | — | US | disclosed |
| EP-1308448-A1 | Method for the preparation of chromanone | Sarawak Medichem Pharmaceuticals Inc. (US) | 2003-05-07 | — | — | EP | disclosed |
| EP-0775130-B1 | METHOD FOR THE PREPARATION OF (+/-)-CALANOLIDE A AND INTERMEDIATES THEREOF | SARAWAK MEDICHEM PHARMACEUTICALS INC (US) | 2003-05-02 | — | — | EP | disclosed |
| EP-1054007-A2 | Method for the preparation of (+/-)-calanolide A | MEDICHEM RESEARCH, INC. (US) | 2000-11-22 | — | — | EP | disclosed |
| EP-0050396-B1 | COUMARIN INTERMEDIATES | BEECHAM GROUP PLC (GB) | 1984-12-27 | — | — | EP | disclosed |
| EP-0010392-B1 | HETEROCYCLIC COUMARIN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID DERIVATIVES | BEECHAM GROUP PLC (GB) | 1982-12-29 | — | — | EP | disclosed |
| EP-0050396-A1 | Coumarin intermediates | BEECHAM GROUP PLC (GB) | 1982-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150335691-A1 | PLANT EXTRACT OBTAINED FROM KIELMEYERA AUREOVINOSA WHICH HAS ANTIBIOTIC ACTIVITY, ISOLATED CHEMICAL COMPOUND, COMPOSITIONS COMPRISING SAME, USES THEREOF AND METHODS FOR PREVENTING AND TREATING BACTERIAL INFECTIONS | AAAS, AK1, ICMT | CA12 3519/4885CA1 4322/4885CA9 929/4885 |
| US-20070173531-A1 | Compound | HSD17B11, NR5A1, CYP17A1 | CA12 864/4885CA1 187/4885CA9 519/4885 |
| US-20050154050-A1 | Compound | HSD17B11, NR5A1, CYP17A1 | CA12 864/4885CA1 187/4885CA9 519/4885 |
| US-20150011619-A1 | METHOD OF TREATMENT FOR ACNE AND AN ANTI-ACNE FORMULATION | PROC, HSD17B10, CYP19A1 | CA12 3562/4885CA1 4847/4885CA9 3840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.